SUP-T1

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA, 95013123, human blood, Lymphoblast

• UNSPSC-Code: 41106514

Eigenschaften

• Biologische Quelle: human blood
• Verpackung: tube of 5 μg 95013123-DNA-5UG; pkg of vial of cells 95013123-1VL
• Wachstumsmodus: Suspension
• Karyotyp: 92XXXY, -2, -2, -9, -9, 2inv(2*)(p21q11), +2inv(2), del(2*)(Q21), 2del(4)(q31q35), 2del (5)(p13p14), 2del(6)(q23q27), inv(14)(q11q32), t(7;9)(q34,q34), +der(9)t(7;9). Undergone Tetraploidisation
• Morphologie: Lymphoblast
• Produkte: Not specified
• Rezeptoren: CD4
• Methode(n): cell culture | mammalian: suitable
• Relevante Krankheit(en): cancer
• Versandbedingung: dry ice
• Lagertemp.: −196°C

Beschreibung

Ursprung der Zelllinie

Human T cell lymphoblastic Lymphoma

Beschreibung der Zelllinie

Derived from a Malignant pleural effusion taken from an eight year old caucasian male with T cell lymphoblastic lymphoma. These cells are E-rosette, Leu 5, OKT9 and CALLA negative. They also express β2M, Leu 1, 2, 3a, 4, 6, 9 and OKT10 antigens and are CD4 positive. These cells are negative for Tac, HLA-DR and surface immunoglobulin.

Anwendung

Cells have been used for growth of HIV-1

SUP-T1 has been used in a study targeting B-cell neoplasia with T-cell receptors recognizing a cluster of differentiation 20 (CD20)-derived peptide on patient-specific human leucocyte antigen (HLA). Existing appl-SUP-T1 cells have been used for growth of HIV-1.

Nährmedium

RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).

Subkultur-Routine

Maintain cultures between 2x100,000 to 2x1,000,000 cells/ml 5% CO₂; 37°C.

Sonstige Hinweise

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