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Merck

C1605

Sigma-Aldrich

Z-Val-Asp(O-Me)-Val-Ala-Asp(O-Me) fluoromethyl ketone

powder, ≥95%

Synonym(e):

Z-VDVAD-FMK

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About This Item

Lineare Formel:
C32H46N5O11F
CAS-Nummer:
Molekulargewicht:
695.73
MDL-Nummer:
UNSPSC-Code:
12352209
PubChem Substanz-ID:
NACRES:
NA.77

Biologische Quelle

synthetic (organic)

Qualitätsniveau

Assay

≥95%

Form

powder

Farbe

white

Löslichkeit

DMSO: soluble

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)OC)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(C)C)C(=O)CF

InChI

1S/C32H46FN5O11/c1-17(2)26(30(44)34-19(5)28(42)35-21(23(39)15-33)13-24(40)47-6)37-29(43)22(14-25(41)48-7)36-31(45)27(18(3)4)38-32(46)49-16-20-11-9-8-10-12-20/h8-12,17-19,21-22,26-27H,13-16H2,1-7H3,(H,34,44)(H,35,42)(H,36,45)(H,37,43)(H,38,46)/t19-,21-,22-,26-,27-/m0/s1

InChIKey

ANTIWMNLIROOQF-IREHUOSBSA-N

Angaben zum Gen

human ... CASP2(835)
mouse ... CASP2(12366)
rat ... CASP2(64314)

Amino Acid Sequence

Z-Val-Asp-OMe-Val-Ala-Asp-OMe-FMK

Biochem./physiol. Wirkung

A cell-permeable inhibitor of caspase-2, which exhibits competitive and irreversible inhibition.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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