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Merck

C0791

Sigma-Aldrich

Monoclonal Anti-Cytokeratin Peptide 13 antibody produced in mouse

clone KS-1A3, ascites fluid

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

ascites fluid

Antikörper-Produkttyp

primary antibodies

Klon

KS-1A3, monoclonal

Enthält

15 mM sodium azide

Speziesreaktivität

human

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect immunofluorescence: 1:100 using formalin-fixed, paraffin-embedded human tissue sections.1
microarray: suitable

Isotyp

IgG1

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... KRT13(3860)

Spezifität

The antibody reacts with squamous, non-keratinized epithelium, transitional epithelium, pseudostratified epithelium, and myoepithelium.

Immunogen

cultured human epidermoid carcinoma cell line A-431.

Anwendung

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Monoclonal Anti-Cytokeratin Peptide 13 antibody produced in mouse is suitable for the following applications:
  • Immunohistochemistry (formalin-fixed, paraffin-embedded sections)
  • Indirect immunofluorescence at a working dilution of 1:100 using formalin-fixed, paraffin-embedded human tissue sections.
  • Microarray

Biochem./physiol. Wirkung

Cytokeratins are proteins of keratin-containing intermediate filaments that provide mechanical support and other additional functions in epithelial cells. It is found in the intracytoplasmic cytoskeleton of epithelial tissue. Epithelial tissue expresses cytokeratin subunits in a specific and stable pattern. Cytokeratins along with vimentin are involved in cell proliferation, migration and differentiation of preodontoblasts and preameloblasts. The intermediate-sized filaments are abundant in human endothelial cells and are mostly of vimentin type.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

F Dupuit et al.
The Journal of clinical investigation, 96(3), 1601-1611 (1995-09-01)
Human nasal polyps from non-CF and delta F 508 homozygous CF patients were used to compare the expression of CFTR and markers epithelial differentiation, such as cytokeratins (CK) and desmoplakins (DP), at the transcriptional and translational levels. mRNA expression was
Debarchana Saha et al.
PloS one, 12(2), e0171084-e0171084 (2017-02-09)
Hemoglobin (Hb) is a major protein involved in transport of oxygen (O2). It consists of Hb-α and Hb-β subunits, which are normally expressed by cells of erythroid lineage. However, till recently, it was not known whether non-erythroid cells like vaginal
Helen M Rigden et al.
PloS one, 11(5), e0156009-e0156009 (2016-05-27)
To quantify the extent of squamous metaplasia in bronchial biopsies and relate it to the presence of chronic obstructive pulmonary disease (COPD), a smoking-related pathology. Bronchial biopsies (n = 15 in each group) from smokers with COPD GOLD stage1 and
Huan He et al.
The Journal of biological chemistry, 290(21), 13567-13577 (2015-04-09)
Squamous cell differentiation requires the coordinated activation and repression of genes specific to the differentiation process; disruption of this program accompanies malignant transformation of epithelium. The exploration of genes that control epidermal proliferation and terminal differentiation is vital to better
Michael Ebsen et al.
Virchows Archiv : an international journal of pathology, 440(5), 512-518 (2002-05-22)
The adenovirus is a non-enveloped DNA virus which may lead to severe diseases of the respiratory tract. In order to study the influence of virus infection on primary cultured peribronchial submucosal gland cells, we performed in vitro infection with human

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