A7755

5α-Androstan-3α,17β-diol

• Synonym(e): 3α,17β-Dihydroxy-5α-androstane, Dihydroandrosterone
• Empirische Formel (Hill-System): C₁₉H₃₂O₂
• CAS-Nummer: 1852-53-5
• Molekulargewicht: 292.46
• EG-Nummer: 217-447-4
• MDL-Nummer: MFCD00003676
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 24278236
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (TLC)
• Qualitätsniveau: 200
• Form: powder
• Arzneimittelkontrolle: USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
• Methode(n): toxicology assay: suitable
• Löslichkeit: methanol: 19.60-20.40 mg/mL, clear, colorless
• Lagertemp.: room temp
• SMILES String: [H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C19H32O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-17,20-21H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,17-,18-,19-/m0/s1
• InChIKey: CBMYJHIOYJEBSB-KHOSGYARSA-N
• Angaben zum Gen: rat ... Ar(24208)

Beschreibung

Anwendung

5α-Androstane-3α,17β-diol (dihydroandrosterone) is a testosterone metabolite. Dihyroandrosterone inhibited the cell growth of seven cancer cell lines while showing weak toxicity on normal cell lines.

Biochem./physiol. Wirkung

Dihydroandrosterone is a testosterone metabolite; affects sperm maturation and survival.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H351,H360FD
• P-Sätze: P201 - P308 + P313
• Gefahreneinstufungen: Carc. 2 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)