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Merck

A6779

Sigma-Aldrich

Adenosine 5′-triphosphate, periodate oxidized sodium salt

≥97%

Synonym(e):

oATP, Adenosine 5′-triphosphate-2′,3′-dialdehyde

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About This Item

Empirische Formel (Hill-System):
C10H14N5O13P3
CAS-Nummer:
Molekulargewicht:
505.17
MDL-Nummer:
UNSPSC-Code:
41106305
eCl@ss:
32160414
PubChem Substanz-ID:
NACRES:
NA.51

Biologische Quelle

bacterial (corynebacterium sp)

Assay

≥97%

Form

powder

Lagertemp.

−20°C

SMILES String

[Na].Nc1ncnc2n(cnc12)[C@H](O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=O)C=O

InChI

1S/C10H14N5O13P3.Na.H/c11-9-8-10(13-4-12-9)15(5-14-8)7(2-17)26-6(1-16)3-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h1-2,4-7H,3H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/t6-,7+;;/m0../s1

InChIKey

IHQATUPGVKMGLT-AUCRBCQYSA-N

Allgemeine Beschreibung

Adenosine 5′-triphosphate 2′,3′ dialdehyde is a derivative of dialdehyde.

Anwendung

Adenosine 5′-triphosphate, periodate oxidized sodium salt has been used:
  • as an antagonist of the purinergic receptor, P2 × 7 to inhibit P2 × 7 pathway
  • as a nonspecific agonist to assess the activity of P2×7-R by the mobilization of Ca2+
  • to evaluate the physiological significance of elevated intracellular ATP levels
  • increased P2rx7 expression for osteoclastogenesis in Flcn-deficient cells

Biochem./physiol. Wirkung

Adenosine 5′-triphosphate 2′,3′ dialdehyde is considered as an inhibitor of P2 × 7 receptor.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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