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A4562

Sigma-Aldrich

5-(N,N-Dimethyl)amiloride hydrochloride

Synonym(e):

3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride, DMA

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About This Item

Empirische Formel (Hill-System):
C8H12ClN7O · HCl
CAS-Nummer:
1214-79-5
Molekulargewicht:
294.14
MDL-Nummer:
MFCD00069207
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24278216
NACRES:
NA.77

Form

powder

Qualitätsniveau

200

Lagertemp.

2-8°C

SMILES String

Cl.CN(C)c1nc(N)c(nc1Cl)C(=O)\N=C(\N)N

InChI

1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H

InChIKey

IIUPTHVVXMBJMQ-UHFFFAOYSA-N

Angaben zum Gen

human ... SCNN1A(6337) , SCNN1B(6338) , SCNN1D(6339) , SCNN1G(6340) , SLC9A1(6548)
mouse ... Scnn1a(20276) , Scnn1b(20277) , Scnn1d(140501) , Scnn1g(20278)
rat ... Scnn1a(25122) , Scnn1b(24767) , Scnn1g(24768) , Slc9a1(24782) , Slc9a2(24783) , Slc9a3(24784)

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Anwendung

5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na2/H+ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain.

Biochem./physiol. Wirkung

Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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