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Weitere Dokumente

53467

Sigma-Aldrich

2,3-Dioleyloxy-1-(dimethylamino)-propan

≥98.0% (TLC)

Synonym(e):

1,2-Dioleyloxy-3-(dimethylamino)-propan, N,N-Dimethyl-2,3-bis-[(9Z)-9-octadecen-1-yloxy]-1-propanamin, DODMA

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About This Item

Empirische Formel (Hill-System):
C41H81NO2
CAS-Nummer:
104162-47-2
Molekulargewicht:
620.09
Beilstein:
10139013
MDL-Nummer:
MFCD22200991
UNSPSC-Code:
12352211
PubChem Substanz-ID:
329757947
NACRES:
NA.85

Biologische Quelle

synthetic

Qualitätsniveau

100

Assay

≥98.0% (TLC)

Form

liquid

Funktionelle Gruppe

amine
ether

Lipid-Typ

cationic lipids

Lagertemp.

−20°C

SMILES String

CCCCCCCC\C=C/CCCCCCCCOCC(CN(C)C)OCCCCCCCC\C=C/CCCCCCCC

InChI

1S/C41H81NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-43-40-41(39-42(3)4)44-38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h19-22,41H,5-18,23-40H2,1-4H3/b21-19-,22-20-

InChIKey

GLGLUQVVDHRLQK-WRBBJXAJSA-N

Verwandte Kategorien

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Lloyd B Jeffs et al.
Pharmaceutical research, 22(3), 362-372 (2005-04-20)
A fully scalable and extrusion-free method was developed to prepare rapidly and reproducibly stabilized plasmid lipid particles (SPLP) for nonviral, systemic gene therapy. Liposomes encapsulating plasmid DNA were formed instantaneously by mixing lipids dissolved in ethanol with an aqueous solution
Yujing Li et al.
Nanomedicine : nanotechnology, biology, and medicine, 13(2), 371-381 (2016-10-18)
Microfluidic systems can accelerate clinical translation of nanoparticles due to their ability to generate nanoparticles in a well-controlled and reproducible manner. In this study, a single-step process based on microfluidic focusing (MF) was employed to synthesize transferrin-conjugated lipid nanoparticles (Tf-LNPs)
Adam Judge et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 13(2), 328-337 (2005-11-09)
The systemic application of nucleic acid drugs requires delivery systems that overcome the poor pharmacokinetics, limited biodistribution, and inefficient uptake of nucleic acids. PEGylated liposomes show considerable promise because of their intrinsic ability to accumulate at disease sites and facilitate
Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids.
Heyes, J., et al.
J. Controlled Release, 107, 276-287 (2005)
Xi Wang et al.
Molecules (Basel, Switzerland), 24(19) (2019-10-03)
Glioma is one of the most aggressive and common malignant brain tumors. Due to the presence of the blood-brain barrier (BBB), the effectiveness of therapeutics is greatly affected. In this work, to develop an efficient anti-glioma drug with targeting and
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