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A1010

Sigma-Aldrich

Arsentrioxid

ReagentPlus®, ≥99.0%

Synonym(e):

Arsen(III)-oxid, Arsenigsäure-anhydrid

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About This Item

Empirische Formel (Hill-System):
As2O3
CAS-Nummer:
1327-53-3
Molekulargewicht:
197.84
EG-Nummer:
215-481-4
MDL-Nummer:
MFCD00003433
UNSPSC-Code:
12171602
PubChem Substanz-ID:
329770647
NACRES:
NA.55

Dampfdruck

0 hPa ( 66 °C)

Produktlinie

ReagentPlus®

Assay

≥99.0%

Form

powder

Lagertemp.

room temp

SMILES String

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChIKey

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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Allgemeine Beschreibung

Arsenic(III) oxide, also known as arsenic trioxide, is an amphoteric oxide that serves as a raw material for the synthesis of several arsenic-based compounds. It is utilized to decolorize glasses and enamels. Its efficacy in treating in acute promyelocytic leukaemia (APL) has been investigated.

Anwendung

Arsenic(III) oxide was used in a study detailing the effect of arsenic trioxide in combination with γ-irradiation to elucidate the hemoglobin (Hb).

Biochem./physiol. Wirkung

Very potent agent against acute promyelocytic leukemia (APL). Causes skin, lung and bladder cancer.

Rechtliche Hinweise

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

Zielorgane

Respiratory system,Cardio-vascular system,Gastrointestinal tract

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Arsenous Acid (AsIII) Standard Solution

NIST3037

Arsenous Acid (AsIII) Standard Solution

Kupfer wire, diam. 0.64 mm, 99.995% trace metals basis

Sigma-Aldrich

326410

Kupfer

Natriumarsenat, zweibasisch Heptahydrat ACS reagent, ≥98%

Sigma-Aldrich

S9663

Natriumarsenat, zweibasisch Heptahydrat

Arsen powder, ≥99.997% trace metals basis

Sigma-Aldrich

267961

Arsen

Combined effect of arsenic trioxide and radiation on physical properties of hemoglobin biopolymer.
Saad-El-Din AA, et al.
Journal of Radiation Research and Applied Sciences, 7(2), 411-416 (2014)
Wilson H Miller et al.
Cancer research, 62(14), 3893-3903 (2002-07-19)
Arsenic trioxide has shown substantial efficacy in treating both newly diagnosed and relapsed patients with acute promyelocytic leukemia (APL). As a single agent, it induces complete remissions, causing few adverse effects and only minimal myelosuppression. These successes have prompted investigations
E Lengfelder et al.
Leukemia, 26(3), 433-442 (2011-09-10)
Arsenic trioxide (ATO) is presently the most active single agent in the treatment of acute promyelocytic leukemia (APL). This review provides insights into the mode of action and the pharmacological properties of ATO, and summarizes the most relevant results of
Dikshith TSS
Handbook of Chemicals and Safety, 92-92 (1992)
Z X Shen et al.
Blood, 89(9), 3354-3360 (1997-05-01)
The therapeutic effect of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL) was evaluated among 15 APL patients at relapse after all-trans retinoic acid (ATRA) induced and chemotherapy maintained complete remission (CR). As2O3 was administered intravenously at
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