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Sigma-Aldrich

Arsentrioxid

ACS reagent (primary standard)

Synonym(e):

Arsen(III)-oxid, Arsenigsäure-anhydrid

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About This Item

Empirische Formel (Hill-System):
As2O3
CAS-Nummer:
1327-53-3
Molekulargewicht:
197.84
EG-Nummer:
215-481-4
MDL-Nummer:
MFCD00003433
UNSPSC-Code:
12171602
PubChem Substanz-ID:
329753664
NACRES:
NB.24

Qualität

ACS reagent (primary standard)

Dampfdruck

0 hPa ( 66 °C)

Assay

99.95-100.05%

Form

powder

Eignung der Reaktion

reagent type: catalyst
core: arsenic

Glührückstand

≤0.02%

Löslichkeit

dilute HCl: insoluble ≤0.01%

Anionenspuren

S2-: passes test (lim. ~0.001%)
chloride (Cl-): ≤0.005%

Kationenspuren

Fe: ≤5 ppm
Pb: ≤0.002%
Sb: ≤0.05%

SMILES String

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChIKey

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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Allgemeine Beschreibung

Arsenic (III) oxide, also referred to as arsenic trioxide, is an amphoteric oxide that is used as a raw material to produce several arsenic-based compounds.

Anwendung

Arsenic (III) oxide is used
  • In the synthesis of arsenic pentafluoride (AsF5) by static fluorination method in a closed system.
  • In the preparation of arsenic-doped ZnO films by adding As2O3 to zinc acetate, 2-methoxyethanol, and monoethanolamine by sol-gel spin coating method.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

Zielorgane

Respiratory system,Cardio-vascular system,Gastrointestinal tract

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Sigma-Aldrich

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Supelco

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Sigma-Aldrich

200077

Arsen(III)-chlorid

Yanfei Jia et al.
PloS one, 8(1), e54774-e54774 (2013-02-06)
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and has
Liangchun Hao et al.
Journal of pediatric hematology/oncology, 35(2), e67-e70 (2013-02-16)
The aim of this study was to investigate the hepatotoxicity induced by arsenic trioxide (As2O3) at a therapeutic dose for pediatric acute promyelocytic leukemia (APL). A total of APL patients received As2O3 treatment by IV drip. Hepatotoxicity was monitored based
Yuhua Fan et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 31(1), 80-91 (2013-02-01)
Arsenic trioxide (As2O3) is a highly effective agent for treatment of acute promyelocytic leukemia (APL). However, consecutively administered As2O3 induces serious adverse cardiac effects, including long QT syndrome (LQTs) and even sudden cardiac death. Previous studies have shown that genistein
Huihui Wang et al.
Environmental toxicology, 28(5), 267-275 (2013-04-17)
Although arsenic is effective in the treatment of acute promyelocytic leukemia (APL), as a well-known environmental toxicant, the side effects of arsenic treatment and arsenic methylation metabolism of the patients are rarely reported. In this manuscript, we investigated 23 APL
Athena Kritharis et al.
Annals of hematology, 92(6), 719-730 (2013-03-16)
For more than 2,000 years, arsenic and its derivatives have shown medical utility. Owing to the toxicities and potential carcinogenicity of arsenicals, their popularity has fluctuated. The exact mechanism of action of therapeutic arsenic is not well characterized but likely
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