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Merck

178810

Sigma-Aldrich

Tetrahydrofuran

≥99.0%, contains 250 ppm BHT as inhibitor, ReagentPlus®

Synonym(e):

Butylenoxid, Oxolan, Tetramethylenoxid

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About This Item

Empirische Formel (Hill-System):
C4H8O
CAS-Nummer:
Molekulargewicht:
72.11
Beilstein:
102391
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12191501
PubChem Substanz-ID:
NACRES:
NA.21
Assay:
≥99.0%
bp:
65-67 °C (lit.)
Dampfdruck:
114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

Produktbezeichnung

Tetrahydrofuran, ReagentPlus®, ≥99.0%, contains 200-400 ppm BHT as inhibitor

Dampfdichte

2.5 (vs air)

Qualitätsniveau

Dampfdruck

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

Produktlinie

ReagentPlus®

Assay

≥99.0%

Form

liquid

Selbstzündungstemp.

610 °F

Enthält

200-400 ppm BHT as inhibitor

Expl.-Gr.

1.8-11.8 %

Brechungsindex

n20/D 1.407 (lit.)

pH-Wert

~7

bp

65-67 °C (lit.)

mp (Schmelzpunkt)

−108 °C (lit.)

Dichte

0.889 g/mL at 25 °C (lit.)

SMILES String

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChIKey

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Allgemeine Beschreibung

Tetrahydrofuran (THF) is a saturated cyclic ether mainly used as an organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. THF constitutes the key fragment of various natural products (polyether antibiotics). THF can form a double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1,4-diol is formed as an intermediate during the synthesis of THF. Hot THF is useful for the dissolution of polyvinylidene chloride (PVDV).

Anwendung

Tetrahydrofuran may be used for the dissolution of poly-ε-caprolactone (PCL) and 1,3-diaminopentane, during the preparation of poly-ε-caprolactone (PCL)-hydroxyapatite (HA) scaffolds and acrylate-terminated poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) (C32)- 1,3-diaminopentane (117) polymer, respectively.

Sonstige Hinweise

For information on tetrahydrofuran miscibility, please visit the following link:
Tetrahydrofuran Miscibility/Immiscibility Table

Greener alternatives are available for many THF applications, 2-Methyltetrahydrofuran (155810) and Cyclopentyl methyl ether (675989)

Read more about THF alternatives:
2-Methyltetrahydroun (2-MeTHF): A biomass-Derived solvent with Broad Applications in Organic Chemistry

The toxicological assessment of cyclopentyl methyl ether (CPME) as a green solvent

Rechtliche Hinweise

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Zielorgane

Central nervous system, Respiratory system

Zusätzliche Gefahrenhinweise

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 1

Flammpunkt (°F)

-6.2 °F - closed cup

Flammpunkt (°C)

-21.2 °C - closed cup


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