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Merck

Y0001262

Flucytosin für die Systemeignung

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

5-Fluorcytosin, 4-Amino-5-fluor-2-hydroxy-pyrimidin, Flucytosin

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About This Item

Empirische Formel (Hill-System):
C4H4FN3O
CAS-Nummer:
Molekulargewicht:
129.09
Beilstein:
127285
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

flucytosine

Hersteller/Markenname

EDQM

mp (Schmelzpunkt)

298-300 °C (dec.) (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

NC1=NC(=O)NC=C1F

InChI

1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)

InChIKey

XRECTZIEBJDKEO-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Flucytosine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Nukleosid-Analogon mit antimykotischen Aktivitäten. 5-FC wird durch Cytosindeaminase zu 5-Fluoruracil deaminiert, was zur RNA Fehlcodierung führt. 5-Fluorcytosin hemmt die DNA- und RNA-Synthese und stört die ribosomale Proteinsynthese.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Ähnliches Produkt

Piktogramme

Health hazard

Signalwort

Warning

H-Sätze

P-Sätze

Gefahreneinstufungen

Repr. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Ya-li Yang et al.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 26, 154-161 (2014-07-27)
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Cheshta Sharma et al.
Mycoses, 57(9), 544-552 (2014-04-05)
We investigated the prevalence of vulvovaginal candidiasis due to C. africana in an STD clinic in India and analysed the genetic relatedness of these C. africana isolates with those outside India. A total of 283 germ-tube-positive yeasts were identified by
Sebastian A Mikolajczak et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 22(9), 1707-1715 (2014-05-16)
Immunization with live-attenuated Plasmodium sporozoites completely protects against malaria infection. Genetic engineering offers a versatile platform to create live-attenuated sporozoite vaccine candidates. We previously generated a genetically attenuated parasite (GAP) by deleting the P52 and P36 genes in the NF54
Hedda Luise Koehling et al.
Journal of clinical microbiology, 53(1), 255-261 (2014-11-14)
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Antimicrobial agents and chemotherapy, 58(8), 4476-4485 (2014-05-29)
We characterized two additional membrane transporters (Fur4p and Dal4p) of the nucleobase cation symporter 1 (NCS1) family involved in the uptake transport of pyrimidines and related molecules in the opportunistic pathogenic yeast Candida lusitaniae. Simple and multiple null mutants were

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