SMB01324

Cyclo(His-Pro)

• Synonym(e): Cyclo(L-histidyl-L-proline), Cyclo(histidyl-proline), Cyclo(prolylhistidine), Histidylproline diketopiperazine, Histidylproline dioxopiperazine, CHP
• Empirische Formel (Hill-System): C₁₁H₁₄N₄O₂
• CAS-Nummer: 53109-32-3
• Molekulargewicht: 234.25
• MDL-Nummer: MFCD00133207
• UNSPSC-Code: 12352209
• NACRES: NA.26

Eigenschaften

• Assay: 98% (HPLC)
• Qualitätsniveau: 100
• Form: solid
• Farbe: white to off-white
• mp (Schmelzpunkt): 162—164 °C
• Versandbedingung: 2-8°C
• Lagertemp.: −20°C
• SMILES String: O=C1N[C@@H](Cc2cnc[nH]2)C(=O)N3CCC[C@@H]13
• InChI: 1S/C11H14N4O2/c16-10-9-2-1-3-15(9)11(17)8(14-10)4-7-5-12-6-13-7/h5-6,8-9H,1-4H2,(H,12,13)(H,14,16)/t8-,9-/m0/s1
• InChIKey: NAKUGCPAQTUSBE-IUCAKERBSA-N

Beschreibung

Allgemeine Beschreibung

Cyclo(His-Pro) is a cyclic dipeptide consisting of the amino acids histidine (His) and proline (Pro). This small peptide forms a closed loop, with histidine and proline connected through a peptide bond. It can be found naturally in certain proteins and peptides and can also be synthesized chemically. This unique molecule is related to thyrotropin-releasing hormone and has various roles in the central nervous system. It serves as a substrate for organic cation transporters, making it essential for neuroprotection. Cyclo(His-Pro) holds promise for therapeutic applications, with the potential to counteract neuroinflammation-based degenerative conditions through both oral and parenteral administration routes. It can inhibit NF-κB nuclear accumulation and influence a range of inflammatory and stress responses, making it a valuable asset in the study of cell biology, biochemical research, and neuroprotection research.

Anwendung

Cyclo(L-His-L-Pro) is a versatile molecule and it finds application in biochemical and metabolomics research.

Leistungsmerkmale und Vorteile

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

Sonstige Hinweise

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Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3