PHR3187

Ifosfamid

pharmaceutical secondary standard, certified reference material

• Synonym(e): Ifosfamid, Ifex, N,3-Bis-(2-chlorethyl)-tetrahydro-2H-1,3,2-oxazaphosphorin-2-amin-2-oxid
• Empirische Formel (Hill-System): C₇H₁₅Cl₂N₂O₂P
• CAS-Nummer: 3778-73-2
• Molekulargewicht: 261.09
• MDL-Nummer: MFCD00057374
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to BP BP759; traceable to USP 1336205
• API-Familie: ifosfamide
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 1 g
• Anwendung(en): pharmaceutical
• Lagertemp.: 2-8°C
• SMILES String: ClCCNP1(=O)OCCCN1CCCl
• InChI: 1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)
• InChIKey: HOMGKSMUEGBAAB-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Ifosfamid ist eine Stickstoff-Senfgas-Verbindung und ein strukturelles Isomer von Cyclophosphamid. Ifosfamid ist ein Prodrug und muss durch das Cytochrom P450 zur biologisch aktiven Komponente transformiert werden. Es wird als antineoplastischer Wirkstoff in der Chemotherapie verwendet, doch die Wahrscheinlichkeit einer Nierentoxizität ist bei Ifosamid größer als bei Cyclophosphamid.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301,H319,H340,H350,H360FD
• P-Sätze: P202 - P264 - P280 - P301 + P310 - P305 + P351 + P338 - P337 + P313
• Gefahreneinstufungen: Acute Tox. 3 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable