PHR1856

Quetiapin-Fumarat

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Quetiapin -hemifumarat (Salz)
• Empirische Formel (Hill-System): C₂₁H₂₅N₃O₂S · 0.5C₄H₄O₄
• CAS-Nummer: 111974-72-2
• Molekulargewicht: 441.54
• MDL-Nummer: MFCD03423782
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. Y0006157; traceable to USP 1592704
• API-Familie: quetiapine
• Form: powder
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 1 g
• Anwendung(en): pharmaceutical
• Lagertemp.: 2-30°C
• SMILES String: OC(=O)\C=C\C(O)=O.OCCOCCN1CCN(CC1)C2=Nc3ccccc3Sc4ccccc24.OCCOCCN5CCN(CC5)C6=Nc7ccccc7Sc8ccccc68
• InChI: 1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+
• InChIKey: ZTHJULTYCAQOIJ-WXXKFALUSA-N
• Angaben zum Gen: human ... DRD2(1813) , HTR2A(3356) , HTR2C(3358)

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Quetiapine hemifumarate is an atypical antipsychotic, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC0140 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H302,H400
• P-Sätze: P273 - P301 + P312 + P330
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Acute 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable