PHR1722

Triamteren

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Triamteren, 6-Phenyl-2,4,7-pteridintriamin
• Empirische Formel (Hill-System): C₁₂H₁₁N₇
• CAS-Nummer: 396-01-0
• Molekulargewicht: 253.26
• EG-Nummer: 206-904-3
• MDL-Nummer: MFCD00006708
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823575
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. Y0000837; traceable to USP 1680007
• API-Familie: triamterene
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 400 mg
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-30°C
• SMILES String: Nc1nc(N)c2nc(-c3ccccc3)c(N)nc2n1
• InChI: 1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)
• InChIKey: FNYLWPVRPXGIIP-UHFFFAOYSA-N
• Angaben zum Gen: human ... SCNN1A(6337) , SCNN1B(6338) , SCNN1G(6340)

Beschreibung

Allgemeine Beschreibung

Triamterene is a potassium-sparing diuretic, which exhibits antihypertensive activity. It is used in combination with thiazide deuretic, such as benzthiazide for treating hypertension and edema associated with mild to moderate congestive heart failure.

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Triamterene may be used as a secondary pharma standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography technique.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA7397 in the slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable