PHR1494

Pilocarpin-Nitrat

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Pilocarpin -nitrat (Salz)
• Empirische Formel (Hill-System): C₁₁H₁₆N₂O₂ · HNO₃
• CAS-Nummer: 148-72-1
• Molekulargewicht: 271.27
• Beilstein: 4171406
• EG-Nummer: 205-723-7
• MDL-Nummer: MFCD00078497
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823416

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to BP 503; traceable to Ph. Eur. P1700000; traceable to USP 1539009
• API-Familie: pilocarpine
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 500 mg
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-30°C
• SMILES String: O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
• InChI: 1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1
• InChIKey: PRZXEPJJHQYOGF-GNAZCLTHSA-N
• Angaben zum Gen: human ... CHRM1(1128) , CHRM3(1131)

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pilocarpine Nitrate is a naturally occurring cholinomimetic drug, exhibiting nicotinic and muscarinic properties. It is widely used for controlling intraocular pressure in glaucoma, immediate relief of mydriasis, and to reverse mydriasis caused by cycloplegic agents.

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Nicht-selektiver muskarinischer Acetylcholin-Rezeptoragonist, verwendet für ein experimentelles Epilepsiemodell.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA3042 in the slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS03,GHS06
• Signalwort: Danger
• H-Sätze: H272 - H302 - H330
• P-Sätze: P210 - P220 - P260 - P264 - P301 + P312 - P304 + P340 + P310
• Gefahreneinstufungen: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Ox. Sol. 2
• Lagerklassenschlüssel: 5.1B - Oxidizing hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable