PHR1021

Clindamycin-Phosphat

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Clindamycin-2-Phosphat, Clindamycin-2-dihydrogenphosphat
• Empirische Formel (Hill-System): C₁₈H₃₄ClN₂O₈PS
• CAS-Nummer: 24729-96-2
• Molekulargewicht: 504.96
• EG-Nummer: 246-433-0
• MDL-Nummer: MFCD07793328
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823052
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. C2269000; traceable to USP 1138008
• API-Familie: clindamycin
• Analysenzertifikat (CofA): current certificate can be downloaded
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: -10 to -25°C
• SMILES String: CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC([C@H](C)Cl)C2O[C@H](SC)[C@H](OP(O)(O)=O)[C@@H](O)[C@H]2O
• InChI: 1S/C18H34ClN2O8PS/c1-5-6-10-7-11(21(3)8-10)17(24)20-12(9(2)19)15-13(22)14(23)16(18(28-15)31-4)29-30(25,26)27/h9-16,18,22-23H,5-8H2,1-4H3,(H,20,24)(H2,25,26,27)/t9-,10+,11-,12?,13+,14-,15?,16+,18+/m0/s1
• InChIKey: UFUVLHLTWXBHGZ-MWBQRTRKSA-N

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Clindamycin is a common antibiotic drug generally employed for the treatment of infections caused by gram-positive aerobes and both gram-negative and gram-positive anaerobic pathogens.

Anwendung

Clindamycin Phosphate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and potentiometry techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Wirkungsspektrum: Gram-positive Kokken und Taxoplasma. Besonders aktiv gegen anaerobe Bakterien.
Wirkmechanismus: Hemmt die Proteinsynthese in Bakterien durch Bindung der 50S ribosomalen Untereinheit

Sonstige Hinweise

Antibakterielles und antiprotozoales Antibiotikum der Lincosamid-Klasse.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC4009 in the slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H317,H319,H362
• P-Sätze: P260 - P263 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Lact. - Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable