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Merck

F8755

Supelco

Fenbufen

analytical standard

Synonym(e):

γ-Oxo-(1,1′-biphenyl)-4-buttersäure

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About This Item

Lineare Formel:
C6H5C6H4CO(CH2)2CO2H
CAS-Nummer:
Molekulargewicht:
254.28
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

184-187 °C (lit.)

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

SMILES String

OC(=O)CCC(=O)c1ccc(cc1)-c2ccccc2

InChI

1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19)

InChIKey

ZPAKPRAICRBAOD-UHFFFAOYSA-N

Angaben zum Gen

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Allgemeine Beschreibung

Fenbufen belongs to the class of non-steroidal anti-inflammatory drugs, widely used as an antipyretic and analgesic in medical applications. Its mode of action involves the inhibition of cyclooxygenase enzyme and thereby prevents the synthesis of certain prostaglandins.

Anwendung

Fenbufen may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Skull and crossbones

Signalwort

Danger

H-Sätze

P-Sätze

Gefahreneinstufungen

Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Bingxin Li et al.
International journal of pharmaceutics, 287(1-2), 89-95 (2004-11-16)
Layered double hydroxides (LDHs) or so-called anionic clays consist of cationic brucite-like layers and exchangeable interlayer anions. Because of their biocompatibility, these layered inorganic solids can be used as host materials to create drug-LDH host-guest supramolecular structures. Because of the
Ho-Lien Huang et al.
Biomaterials, 34(13), 3355-3365 (2013-02-07)
This study is concerned with the development of an agent for single photon emission computer tomography (SPECT) for imaging inflammation and tumor progression. [(123)I]Iodooctyl fenbufen amide ([(123)I]IOFA) was prepared from the precursor N-octyl-4-oxo-4-(4'-(trimethylstannyl)biphenyl-4-yl)butanamide with a radiochemical yield of 15%, specific
Z X Meng et al.
Colloids and surfaces. B, Biointerfaces, 84(1), 97-102 (2011-01-14)
Drug (Fenbufen, FBF)-loaded poly(D,L-lactide-co-glycolide) (PLGA) and PLGA/gelatin nanofibrous scaffolds were fabricated via electrospinning technique. The influences of gelatin content, fiber arrangement, crosslinking time and pH value of the buffer solution on FBF release behavior of the resulting nanofibrous scaffolds were
I Bratu et al.
Biopolymers, 77(6), 361-367 (2005-02-04)
1H-NMR spectra of aqueous solutions of fenbufen and two cyclodextrins (alpha- or gamma-cyclodextrin, respectively) mixtures confirm the formation of an inclusion complex if gamma-cyclodextrin is used, whereas in the case of alpha-cyclodextrin no inclusion complex was obtained. The stoichiometry of
Interstitial nephritis, toxic epidermal necrolysis and liver dysfunction associated to fenbufen.
N Krivoy et al.
Clinical rheumatology, 16(5), 489-490 (1997-11-05)

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