C5548

Clobetasonbutyrat

≥98% purity, powder

• Synonym(e): 21-Chlor-9-fluor-17-hydroxy-16-methylpregna-1,4-dien-3,11,20-trion-17-butyrat
• Empirische Formel (Hill-System): C₂₆H₃₂ClFO₅
• CAS-Nummer: 25122-57-0
• Molekulargewicht: 478.98
• EG-Nummer: 246-635-9
• MDL-Nummer: MFCD00133196
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 329775093
• NACRES: NA.47

Eigenschaften

• Produktbezeichnung: Clobetasonbutyrat, ≥98%
• Qualitätsniveau: 200
• Assay: ≥98%
• Form: powder
• Farbe: white to faint yellow cast
• mp (Schmelzpunkt): 90-100 °C
• Löslichkeit: chloroform: 50 mg/mL, clear, faintly yellow
• ε (Extinktionskoeffizient): 13.4 at 243 nm in chloroform
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: room temp
• SMILES String: CCCC(=O)O[C@@]1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@]12C)C(=O)CCl
• InChI: 1S/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1
• InChIKey: FBRAWBYQGRLCEK-AVVSTMBFSA-N

Beschreibung

Allgemeine Beschreibung

Clobetasone butyrate is a corticosteroid.

Anwendung

Clobetasone butyrate has been used as an internal standard for the quantitative assay of clobetasol propionate.

Clobetasone butyrate has been used to analyze its bio-concentration factor (BCF) in Cyprinus carpio.

Biochem./physiol. Wirkung

Clobetasone butyrate is a potent topical corticosteroid and is primarily used to treat atopic dermatitis (AD). Low dosage of this drug is used to treat dry eye in Sjogrens syndrome.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges