BP1083

Isoniazid

British Pharmacopoeia (BP) Reference Standard

• Synonym(e): 4-Pyridincarbonsäurehydrazid, INH, Isonicotinsäurehydrazid
• Empirische Formel (Hill-System): C₆H₇N₃O
• CAS-Nummer: 54-85-3
• Molekulargewicht: 137.14
• Beilstein: 119374
• MDL-Nummer: MFCD00006426
• UNSPSC-Code: 41116107

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: isoniazid
• Form: powder
• Haltbarkeit: limited shelf life, expiry date on the label
• Hersteller/Markenname: BP
• mp (Schmelzpunkt): 171-173 °C (lit.)
• Anwendung(en): pharmaceutical
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: NNC(=O)c1ccncc1
• InChI: 1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
• InChIKey: QRXWMOHMRWLFEY-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Isoniazid BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Isoniazid Oral Solution

Biochem./physiol. Wirkung

Antibiotikum für die Behandlung von Mycobacterium tuberculosis; inhibiert die Mycolsäure-Biosynthese. Wird von hepatischer N-Acetyltransferase (NAT) und Cytochrom P450 2E1 (CYP2E1) zu Hepatotoxinen metabolisert. Induziert selektiv die Expression von CYP2E1. Inhibiert Aktivitäten von CYP2C19 und CYP3A4 reversibel und inaktiviert CYP1A2, CYP2A6, CYP2C19 und CYP3A4 bei klinisch relevanten Konzentrationen.

Verpackung

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 - H315
• P-Sätze: P264 - P280 - P301 + P312 - P302 + P352 - P332 + P313 - P362 + P364
• Gefahreneinstufungen: Acute Tox. 4 Oral - Skin Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3