938963

Potassium tert-butoxide ChemBeads

• Synonym(e): Potassium tert-butylate, Potassium t-butoxide
• Empirische Formel (Hill-System): KOC₄H₉
• CAS-Nummer: 865-47-4
• Molekulargewicht: 112.21
• MDL-Nummer: MFCD00012162
• UNSPSC-Code: 12352100

Eigenschaften

• Beschreibung: Reagent Type-Organic Salt
• Qualitätsniveau: 100
• Form: solid
• Zusammensetzung: wt% loading of base, 14-16 wt. %
• Eignung der Reaktion: core: potassium
• SMILES String: [K+].CC(C)(C)[O-]
• InChI: 1S/C4H9O.K/c1-4(2,3)5;/h1-3H3;/q-1;+1
• InChIKey: LPNYRYFBWFDTMA-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Potassium tert-butoxide is a strong alkoxide base, it can deprotonate carbon and other Brφnsted acids. It is a relatively poor nucleophile.

Anwendung

Potassium tert-butoxide has been used as a strong base in the enantioselective synthesis of amines by transfer hydrogenation of N-(tertbutylsulfinyl)imines. It can also be used: To synthesize aliphatic and aromatic amides from corresponding esters and amines. As a base in the intramolecular cyclization of aryl ethers, amines, and amides. As a catalyst to prepare styrene derivatives from aryl halides and alkenes by Mizoroki-Heck reaction.
For general uses, product is also available in powdered form (156671)

Leistungsmerkmale und Vorteile

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

Sonstige Hinweise

High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads

Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughput Experimentation

ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

Sicherheitshinweise

• Piktogramme: GHS02,GHS05
• Signalwort: Danger
• H-Sätze: H228,H252,H314
• P-Sätze: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 2 - Skin Corr. 1A
• Zusätzliche Gefahrenhinweise: EUH014
• Lagerklassenschlüssel: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 3