Direkt zum Inhalt
Merck

76526

Supelco

L-Leucin

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonym(e):

(S)-2-Amino-4-methylpentansäure

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Lineare Formel:
(CH3)2CHCH2CH(NH2)CO2H
CAS-Nummer:
Molekulargewicht:
131.17
Beilstein:
1721722
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
eCl@ss:
32160406
PubChem Substanz-ID:
E-Nummer:
E641
NACRES:
NA.24

Qualität

certified reference material
TraceCERT®

Qualitätsniveau

Produktlinie

TraceCERT®

chemische Klasse(n) des Analyten

amino acids, peptides, proteins

Hersteller/Markenname

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Farbe

white

mp (Schmelzpunkt)

>300 °C (lit.)

Anwendung(en)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

Format

neat

Lagertemp.

20-25°C

SMILES String

CC(C)C[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1

InChIKey

ROHFNLRQFUQHCH-YFKPBYRVSA-N

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Allgemeine Beschreibung

L-Leucine is an important and essential branched chain amino acid. It shows activity with the mechanistic target of rapamycin(mTOR) pathway, involved in the synthesis of proteins and satiety.
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Check out the entire portfolio of our amino acids certified reference materials (CRM)

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Rechtliche Hinweise

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

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Anwendung

Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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Slide 1 of 9

1 of 9

Fleck M and Petrosyan.MA et al.
Salts of Amino Acids: Crystallization, Structure and Properties (2014)
Mullin.EG, et al. et al.
Integrative Weight Management: A Guide for Clinicians (2014)
William I A Haynes et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(11), 4804-4814 (2013-03-15)
The identification of a hyperdirect cortico-subthalamic nucleus connection highlighted the important role of the subthalamic nucleus (STN) in regulating behavior. However, this pathway was shown primarily from motor areas. Hyperdirect pathways associated with cognitive and motivational cortical regions are particularly
Qian Wang et al.
Journal of the National Cancer Institute, 105(19), 1463-1473 (2013-09-21)
L-type amino acid transporters (LATs) uptake neutral amino acids including L-leucine into cells, stimulating mammalian target of rapamycin complex 1 signaling and protein synthesis. LAT1 and LAT3 are overexpressed at different stages of prostate cancer, and they are responsible for
T Yoshimasa et al.
The Journal of clinical investigation, 69(3), 643-650 (1982-03-01)
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with

Protokolle

Separation of L-Alanine; Glycine; L-Valine; L-Leucine; L-Isoleucine; L-Proline; L-Methionine; L-Serine; L-Threonine; L-Phenylalanine; L-Aspartic acid; L-4-Hydroxyproline; L-Cysteine; L-Glutamic acid; L-Asparagine; L-Lysine; L-Glutamine; L-Histidine; L-Tyrosine; L-Tryptophan; L-Cystine

Chromatograms

application for HPLC

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