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Merck

35394

Supelco

Albendazolsulfon

VETRANAL®, analytical standard

Synonym(e):

[5-(Propylsulfonyl)-1H-benzimidazol-2-yl]-carbaminsäure-methylester

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About This Item

Empirische Formel (Hill-System):
C12H15N3O4S
CAS-Nummer:
Molekulargewicht:
297.33
Beilstein:
8394880
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

CCCS(=O)(=O)c1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O4S/c1-3-6-20(17,18)8-4-5-9-10(7-8)14-11(13-9)15-12(16)19-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChIKey

CLSJYOLYMZNKJB-UHFFFAOYSA-N

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Allgemeine Beschreibung

Albendazole sulfone is a nonactive metabolite of albendazole sulfoxide (ABZSO).

Anwendung

Albendazole sulfone may be used as a reference standard in the determination of albendazole sulfone in plasma samples using high-performance liquid chromatography (HPLC) technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Health hazardEnvironment

Signalwort

Warning

Gefahreneinstufungen

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral

Zielorgane

Adrenal gland,spleen,male reproductive organs,Blood

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Victoria Miró et al.
Xenobiotica; the fate of foreign compounds in biological systems, 50(4), 408-414 (2019-07-16)
Combinations of bioactive phytochemicals with synthetic compounds have been suggested as promissory tools for the improvement of nematode control in livestock. Bioactive phytochemicals may interfere with the activity of drug-metabolizing enzymes and delay the metabolic conversion of anthelmintics into less
Constant Edi et al.
PLoS neglected tropical diseases, 13(5), e0007325-e0007325 (2019-05-21)
A single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used for mass drug administration programs for
Zenaís Busatto et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(4), 509-519 (2016-12-17)
This paper describes the development of analytical methods for the quantification of albendazole (ABZ) in fish feed and ABZ and its main known metabolites (albendazole sulfoxide, albendazole sulfone and albendazole aminosulfone) in fish fillet employing LC-MS/MS. In order to assess
Simultaneous determination of albendazole sulfoxide enantiomers and albendazole sulfone in plasma.
Lanchote LV, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 709(2), 273-279 (1998)
Noemi Cowan et al.
International journal for parasitology. Drugs and drug resistance, 7(2), 159-173 (2017-04-04)
Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug uptake into gastrointestinal nematodes responsible for the pharmacological effect are unknown. We assessed

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