5.08773

PPACK, 2HCl

InSolution, ≥88%

• Synonym(e): InSolution PPACK, 2HCl, D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone, 2HCl, H-D-Phe-Pro-Arg-chloromethylketone, 2HCl, PPACK, dihydrochloride InSolution
• Empirische Formel (Hill-System): C₂₁H₃₁ClN₆O₃ · 2HCl
• Molekulargewicht: 523.88
• UNSPSC-Code: 12352202
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥88% (HPLC)
• Form: liquid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; avoid repeated freeze/thaw cycles; protect from light
• Lagertemp.: −70°C

Beschreibung

Allgemeine Beschreibung

D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone (PPACK) is a potent and specific inhibitor of thrombin with ideal, unbiased properties for use as an anticoagulant in blood gas, electrolyte, and iCa analyses.

Biochem./physiol. Wirkung

Reversible: no

Verpackung

Packaged under inert gas

Warnhinweis

Toxicity: Standard Handling (A)

Physikalische Form

A 25 mM (5 mg/357 µl) sterile-filtered solution of PPACK, 2HCl (Cat. No. 520222) in H₂O.

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.

Sonstige Hinweise

Rosado, J. A., et al. 2002. J. Biol. Chem.277, 42157.
Odake S., et al. 1995. J. Enzyme Inhib.9, 17.
Arni, R.K., et al. 1993. Biochemistry32, 4727.
Yamashita, T., et al. 1993. Thromb. Res.69, 93.
Schmaier, A.H., et al. 1992. Thromb. Res.67, 479.
Collen, D., et al. 1982. J. Lab. Clin. Med.99, 76.

Kettner, C., and Shaw, E. 1981. Methods Enzymol.80, 826.
Kettner, C., and Shaw, E. 1979. Thromb. Res.14, 969.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany