14-746M-M

Src (1-530) Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells. For use in Kinase Assays.

• UNSPSC-Code: 12352200
• eCl@ss: 32160405
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Qualitätsniveau: 100
• Rekombinant: expressed in baculovirus infected Sf21 cells
• Mol-Gew.: M_w 61.7 kDa
• Hersteller/Markenname: Upstate^®
• Methode(n): activity assay: suitable (kinase)
• GenBank-Hinterlegungsnummer: K03218
• UniProt-Hinterlegungsnummer: P05480 (mouse); P12931; Q9WUD9 (rat)
• Angaben zum Gen: human ... SRC(6714)

Beschreibung

Allgemeine Beschreibung

N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells.

Product Source: Expressed by baculovirus in Sf21 insect cells.

The mutant form of Src (Src, 1-530) has been identified in cases of advanced colon cancer. This truncating mutation generates an open active form of Src that has been found to be transforming, tumorigenic and metastasis promoting.

Anwendung

Research Category
Stoffwechsel

Research Sub Category
Cardiovascular Disease

Metabolic Disorders

Biochem./physiol. Wirkung

Protein Target: Src

Target Sub-Family: TK

Verpackung

Also available in 10 μg size (cat#14-746) and in bulk (cat# 14-746-K).

Physikalische Form

Ni²⁺/NTA-agarose

50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution

Lagerung und Haltbarkeit

6 months at -70°C from date of shipment.

Sonstige Hinweise

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Rechtliche Hinweise

GenBank is a registered trademark of United States Department of Health and Human Services

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317
• P-Sätze: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Gefahreneinstufungen: Skin Sens. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable