07-503
Anti-p40-phox Antibody
Upstate®, from rabbit
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About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
rabbit
Qualitätsniveau
Antikörperform
purified antibody
Antikörper-Produkttyp
primary antibodies
Klon
polyclonal
Speziesreaktivität
rat, human
Hersteller/Markenname
Upstate®
Methode(n)
western blot: suitable
Isotyp
IgG
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
dry ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
human ... NCF4(4689)
rat ... Ncf4(500904)
Spezifität
p40-phox
Immunogen
C-terminal 6HIS-tagged fusion protein corresponding to full length human p40-phox
Anwendung
Research Category
Neurowissenschaft
Neurowissenschaft
Research Sub Category
Oxidativer Stress
Oxidativer Stress
Anti-p40-phox Antibody is an antibody against p40-phox for use in WB.
Qualität
routinely evaluated by immunoblot in RIPA lysates of HL-60 cells.
Zielbeschreibung
40kDa
Physikalische Form
Protein A purified
Format: Purified
Protein A purified antibody in 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.
Lagerung und Haltbarkeit
Stable for 1 year at 2-8°C from date of receipt.
Rechtliche Hinweise
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 1
Analysenzertifikate (COA)
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F B Wientjes et al.
The Biochemical journal, 296 ( Pt 3), 557-561 (1993-12-15)
The NADPH oxidase generates superoxide in phagocytic cells. It is important for immunity and its deficiency leads to chronic granulomatous disease (CGD). It consists of a membrane-bound flavocytochrome b that lies dormant until activated by the translocation to the plasma
Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin.
Harten SK, Shukla D, Barod R, Hergovich A, Balda MS, Matter K, Esteban MA, Maxwell PH.
Molecular Biology of the Cell null
A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis.
Li, XJ; Tian, W; Stull, ND; Grinstein, S; Atkinson, S; Dinauer, MC
Molecular Biology of the Cell null
Chronic Granulomatous Disease-Like Presentation of a Child with Autosomal Recessive PKCδ Deficiency.
Anna-Lena Neehus et al.
Journal of clinical immunology, 42(6), 1244-1253 (2022-05-19)
Autosomal recessive (AR) PKCδ deficiency is a rare inborn error of immunity (IEI) characterized by autoimmunity and susceptibility to bacterial, fungal, and viral infections. PKCδ is involved in the intracellular production of reactive oxidative species (ROS). We studied a 5-year
Hassan Dakik et al.
Antioxidants (Basel, Switzerland), 10(3) (2021-04-04)
In acute myeloid leukemia (AML), a low level of reactive oxygen species (ROS) is associated with leukemic stem cell (LSC) quiescence, whereas a high level promotes blast proliferation. ROS homeostasis relies on a tightly-regulated balance between the antioxidant and oxidant
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