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Key Documents

04-004

Sigma-Aldrich

Anti-SOCS3 Antibody, clone 1B2

clone 1B2, Upstate®, from mouse

Synonym(e):

suppressor of cytokine signaling 3, ATOD4, CIS3, Cish3, MGC71791, SOCS-3, SSI-3, SSI3

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

1B2, monoclonal

Speziesreaktivität

mouse, human

Hersteller/Markenname

Upstate®

Methode(n)

western blot: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NM_003955.3

UniProt-Hinterlegungsnummer

O14543

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... SOCS3(9021)

Spezifität

Recognizes SOCS3.

Immunogen

mouse SOCS3 recombinant GST fusion protein encompassing amino acids 2-44.

Anwendung

Research Sub Category
Neuroregenerative Medizin

Entwicklungsneurowissenschaft
This Anti-SOCS3 Antibody, clone 1B2 is validated for use in WB for the detection of SOCS3.

Qualität

Routinely evaluated by immunoblot.

Zielbeschreibung

25 kDa

Physikalische Form

Format: Purified
Protein G Purified mouse monoclonal IgG in a solution of 50% glycerol, 0.02 M Phosphate buffer, pH 7.6, 0.25 M NaCl, 0.1% sodium azide as a preservative.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Daniel J Ham et al.
American journal of physiology. Endocrinology and metabolism, 310(11), E970-E981 (2016-04-21)
Amino acids, especially leucine, potently stimulate protein synthesis and reduce protein breakdown in healthy skeletal muscle and as a result have received considerable attention as potential treatments for muscle wasting. However, the normal anabolic response to amino acids is impaired
Evdokia Dimitriadis et al.
Endocrinology, 147(8), 3809-3817 (2006-05-20)
The differentiation of endometrial stromal cells into decidual cells (decidualization) is critical for embryo implantation, but the mechanisms remain poorly defined. Numerous paracrine agents including IL-11 promote human endometrial stromal cell (HESC) decidualization. IL-11 signaling is transduced by the signal
Sam Ansari et al.
Scientific data, 3, 150077-150077 (2016-01-06)
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of an aerosol derived from a prototype
Kate D Sutherland et al.
Oncogene, 23(46), 7726-7733 (2004-09-14)
Suppressor of cytokine signaling (SOCS) proteins have emerged as critical attenuators of cytokine-mediated processes, suggesting a role in the suppression of tumorigenesis. In the ovary and mammary gland, cytokines such as prolactin and IL-6 are important regulators of growth and
Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains.
Cabanski, M; Fields, B; Boue, S; Boukharov, N; DeLeon, H; Dror, N; Geertz, M; Guedj et al.
Inflammation Research null
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