F-044

Flurazepam-D₄ solution

100 μg/mL in methanol, certified reference material, Cerilliant^®

• Empirische Formel (Hill-System): C₂₁H₁₉D₄ClFN₃O
• Molekulargewicht: 391.90
• MDL-Nummer: MFCD00057324
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Qualitätsniveau: 300
• Form: liquid
• Leistungsmerkmale: Snap-N-Spike^®/Snap-N-Shoot^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• drug control: psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• Konzentration: 100 μg/mL in methanol
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): clinical testing
• Format: single component solution
• Lagertemp.: −20°C
• SMILES String: CCN(CC)CCN1C(=O)CN=C(c2ccccc2F)c3cc(Cl)ccc13
• InChI: 1S/C21H23ClFN3O/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23/h5-10,13H,3-4,11-12,14H2,1-2H3
• InChIKey: SAADBVWGJQAEFS-UHFFFAOYSA-N
• Angaben zum Gen: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

Beschreibung

Allgemeine Beschreibung

Flurazepam is a long acting benzodiazepine that is used to treat mild to moderate insomnia. This stable-labeled internal standard is suitable for quantitation of flurazepam levels in GC/MS or LC/MS methods for clinical toxicology, forensic analysis, urine drug testing, pain prescription monitoring or isotope dilution applications.

Anwendung

• Flurazepam-D₄ Solution for Receptor Binding Studies: The application of Flurazepam-D₄ in receptor binding studies, especially for benzodiazepine receptors, provides valuable insights into the dynamics and pharmacology of this drug class, enhancing the understanding of sedative mechanisms similar to those discussed in recent receptor-focused research (Beil-Hildebrand et al., 2024).


• Stable Isotope-Labeled Flurazepam for Quantitative Analysis: Flurazepam-D₄ serves as a precise internal standard in mass spectrometry, enabling accurate quantification of benzodiazepines in complex biological matrices, which is critical for both therapeutic monitoring and forensic investigations, akin to methodologies detailed in analytical chemistry literature (Blanchard et al., 2024).


• High-Purity Flurazepam-D₄ Solution for Drug Metabolism Studies: Utilizing high-purity deuterated derivatives like Flurazepam-D₄ enhances the reliability of drug metabolism studies, facilitating the detailed mapping of metabolic pathways and potential interactions within the body, echoing the precision required in pharmaceutical reviews and metabolic profiling (Dai et al., 2024).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H225,H301 + H311 + H331,H370
• P-Sätze: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Zielorgane: Eyes
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 49.5 °F - closed cup
• Flammpunkt (°C): 9.7 °C - closed cup