999998P

06:0 Diether PC

Avanti Research^™ - A Croda Brand 999998P, powder

• Synonym(e): 1,2-di-O-hexyl-sn-glycero-3-phosphocholine
• Empirische Formel (Hill-System): C₂₀H₄₄NO₆P
• CAS-Nummer: 79645-39-9
• Molekulargewicht: 425.54
• MDL-Nummer: MFCD02259319
• UNSPSC-Code: 51191904
• NACRES: NA.25

Eigenschaften

• Form: powder
• Verpackung: pkg of 1 × 10 mg (999998P-10mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 999998P
• Lipid-Typ: cardiolipins; phospholipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCC)COCCCCCC)=O
• InChI: 1S/C20H44NO6P/c1-6-8-10-12-15-24-18-20(25-16-13-11-9-7-2)19-27-28(22,23)26-17-14-21(3,4)5/h20H,6-19H2,1-5H3/t20-/m1/s1

Beschreibung

Allgemeine Beschreibung

06:0 Diether PC (phosphocholine) is a glycerophospholipid having two hexane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

Anwendung

06:0 Diether PC or 1,2-di-O-hexyl-sn-glycero-3-phosphocholine might be used:

• in bicelle media to measure the H—C one-bond residual dipolar couplings for trisaccharides, Lewis X (Lex) and Lewis A (Lea) methyl glycosides using nuclear magnetic resonance (NMR) residual dipolar couplings
• to compose isotropically tumbling small bicelles, to study its size and morphology by 31P NMR and atomic force microscopy (AFM)
• in bicelle preparation for NMR studies

Biochem./physiol. Wirkung

06:0 Diether PC (phosphocholine) is useful for bicelles preparation. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Incorporating 06:0 Diether PC in bicelles results in bicelles similar to conventional phospholipid bicelles but with improved chemical stability.

Verpackung

5 mL Clear Glass Sealed Ampule (999998P-10mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3