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860634P

Avanti

C16 Dihydroceramide (d18:0/16:0)

Avanti Research - A Croda Brand 860634P, powder

Synonym(e):

N-palmitoyl-D-erythro-sphinganine

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About This Item

Empirische Formel (Hill-System):
C34H69NO3
CAS-Nummer:
Molekulargewicht:
539.92
MDL-Nummer:
UNSPSC-Code:
12352211
NACRES:
NA.25

Form

powder

Verpackung

pkg of 1 × 10 mg (860634P-10mg)
pkg of 1 × 5 mg (860634P-5mg)

Hersteller/Markenname

Avanti Research - A Croda Brand 860634P

Lipid-Typ

sphingolipids

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC

InChI

1S/C34H69NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h32-33,36-37H,3-31H2,1-2H3,(H,35,38)/t32-,33+/m0/s1

InChIKey

GCGTXOVNNFGTPQ-JHOUSYSJSA-N

Anwendung

C16 Dihydroceramide (d18:0/16:0) is suitable for use to study the potential relevance of the changes observed in the sphingolipid composition of autophagosomes and autolysosomes in tetrahydrocannabinol (THC) treated cells or to destabilize biological membranes.

Biochem./physiol. Wirkung

Dihydroceramide acts as a precursor for ceramide synthesis. It has an ability to induce autophagy in the perinuclear region. Dihydroceramide affects autophagic flux and enhances the formation lipid droplets. Accumulation of C16-dihydroceramides might lead to liver injury.

Verpackung

5 mL Amber Glass Screw Cap Vial (860634P-10mg)
5 mL Amber Glass Screw Cap Vial (860634P-5mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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Kunden haben sich ebenfalls angesehen

Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
Hernandez-Tiedra S, et al.
Autophagy, 12(11), 2213-2229 (2016)
Md Abdullah Al Sazzad et al.
Langmuir : the ACS journal of surfaces and colloids, 32(23), 5973-5980 (2016-05-25)
To better understand the interactions of saturated ceramides with unsaturated glycerophospholipids in bilayer membranes, we measured how palmitoyl ceramide (PCer) and dihydroceramide (dihydro-PCer, lacking the trans 4 double bond of the sphingoid base of ceramide) can interact with phosphatidylcholines (PCs)
Dihydroceramide is a key metabolite that regulates autophagy and promotes fibrosis in hepatic steatosis model
Lee Ah young, et al.
Biochemical and biophysical research communications, 494(3-4), 460-469 (2017)
Sonia Hernández-Tiedra et al.
Autophagy, 12(11), 2213-2229 (2016-11-02)
Autophagy is considered primarily a cell survival process, although it can also lead to cell death. However, the factors that dictate the shift between these 2 opposite outcomes remain largely unknown. In this work, we used Δ9-tetrahydrocannabinol (THC, the main

Global Trade Item Number

SKUGTIN
860634P-5MG4061835318810
860634P-10MG

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