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860355P

Avanti

16:0 PC-d62

Avanti Research™ - A Croda Brand 860355P, powder

Synonym(e):

1,2-dipalmitoyl-d62-sn-glycero-3-phosphocholine

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About This Item

Empirische Formel (Hill-System):
C40H18NO8PD62
CAS-Nummer:
25582-63-2
Molekulargewicht:
796.42
UNSPSC-Code:
12352100
NACRES:
NA.25

Assay

>99% (TLC)

Form

powder

Verpackung

pkg of 1 × 10 mg (860355P-10mg)
pkg of 1 × 100 mg (860355P-100mg)
pkg of 1 × 200 mg (860355P-200mg)
pkg of 1 × 25 mg (860355P-25mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 860355P

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COC(C([2H])([2H

InChI

1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1/i1D3,2D3,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,15D2,16D2,17D2,18D2,19D2,20D2,21D2,22D2,23D2,24D2,25D2,26D2,27D2,28D2,29D2,30D2,31D2,32D2,33D2

InChIKey

KILNVBDSWZSGLL-PWXLRKPBSA-N

Verwandte Kategorien

Allgemeine Beschreibung

16:0 PC-d62 is a deuterated phosphocholine (PC) in which 62 protons of dipalmitoyl are replaced by deuterium.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Anwendung

16:0 PC-d62 may be used for the preparation of asymmetric large unilamellar vesicles (aLUVs) for use as cell membrane models.

Verpackung

5 mL Amber Glass Screw Cap Vial (860355P-100mg)
5 mL Amber Glass Screw Cap Vial (860355P-10mg)
5 mL Amber Glass Screw Cap Vial (860355P-200mg)
5 mL Amber Glass Screw Cap Vial (860355P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Lagerklassenschlüssel

11 - Combustible Solids

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Preparation of asymmetric phospholipid vesicles for use as cell membrane models
Doktorova M, et al.
Nature Protocols, 13(9), 2086-2101 (2018)
Kalliopi-Kelli A Vandera et al.
Molecular pharmaceutics, 17(7), 2354-2369 (2020-05-01)
Gram-negative bacteria possess numerous defenses against antibiotics, due to the intrinsic permeability barrier of their outer membrane (OM), explaining the recalcitrance of some common and life-threatening infections. We report the formulation of a new drug, PPA148, which shows promising activity
Drew Marquardt et al.
Langmuir : the ACS journal of surfaces and colloids, 33(15), 3731-3741 (2017-01-21)
We measured the transbilayer diffusion of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in large unilamellar vesicles, in both the gel (Lβ') and fluid (Lα) phases. The choline resonance of headgroup-protiated DPPC exchanged into the outer leaflet of headgroup-deuterated DPPC-d13 vesicles was monitored using 1H
Mitchell DiPasquale et al.
Biochimica et biophysica acta. Biomembranes, 1862(8), 183189-183189 (2020-01-19)
The antioxidant vitamin E is a commonly used vitamin supplement. Although the multi-billion dollar vitamin and nutritional supplement industry encourages the use of vitamin E, there is very little evidence supporting its actual health benefits. Moreover, vitamin E is now
M Orczyk et al.
Langmuir : the ACS journal of surfaces and colloids, 33(15), 3871-3881 (2017-03-24)
Digitonin, a steroidal saponin obtained from the foxglove plant (Digitalis purpurea), displays a wide spectrum of biological properties and is often used as a model in mechanistic investigations of the biological activity of saponins. In the present study, Langmuir monolayers
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