810250C

25-NBD Cholesterol

Avanti Polar Lipids 810250C

• Synonym(e): 25-[N-[(7-nitro-2-1,3-benzoxadiazol-4-yl)methyl]amino]-27-norcholesterol
• Empirische Formel (Hill-System): C₃₃H₄₈N₄O₄
• CAS-Nummer: 105539-27-3
• Molekulargewicht: 564.76
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: liquid
• Verpackung: pkg of 1 × 1 mL (810250C-10mg); pkg of 1 × 1 mL (810250C-1mg); pkg of 1 × 1 mL (810250C-5mg)
• Hersteller/Markenname: Avanti Polar Lipids 810250C
• Konzentration: 1 mg/mL (810250C-1mg); 10 mg/mL (810250C-10mg); 5 mg/mL (810250C-5mg)
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• InChI: 1S/C33H48N4O4/c1-20(7-6-8-21(2)36(5)28-13-14-29(37(39)40)31-30(28)34-41-35-31)25-11-12-26-24-10-9-22-19-23(38)15-17-32(22,3)27(24)16-18-33(25,26)4/h9,13-14,20-21,23-27,38H,6-8,10-12,15-19H2,1-5H3/t20-,21?,23+,24+,25+,26+,27+,32+,33-/m1/s1
• InChIKey: RMGLSQAGXRZCPZ-OVHOIDCTSA-N

Beschreibung

Allgemeine Beschreibung

25-NBD Cholesterol is a fluorescent derivative of cholesterol. Its fluorescent property is due to presence of NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) group.

Anwendung

25-NBD Cholesterol can be used as a labeling agent for confocal microscopy in studying endosomal trafficking and vesicle formation.

Biochem./physiol. Wirkung

Cholesterol is synthesized via a cascade of enzymatic reactions known as the mevalonate pathway. Cholesterol plays a major role in the architecture and stability of the plasma membrane and is also involved in the synthesis of cholecalciferol (Vitamin D3). Cholesterol build up on the walls or arteries causes obstruction of blood flow leading to a serious condition called artherosclerosis. It is a precursor for bile acid and for the synthesis of steroid hormones like progesterone, testosterone, cortisol, and aldosterone.

Verpackung

5 mL Clear Glass Sealed Ampule (810250C-10mg)

5 mL Clear Glass Sealed Ampule (810250C-1mg)

5 mL Clear Glass Sealed Ampule (810250C-5mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372
• P-Sätze: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): does not flash
• Flammpunkt (°C): does not flash