700070P

trihydroxycholestanoic acid

Avanti Research^™ - A Croda Brand

• Synonym(e): 3α,7α,12α-trihydroxycholestanoic acid
• Empirische Formel (Hill-System): C₂₇H₄₆O₅
• CAS-Nummer: 547-98-8
• Molekulargewicht: 450.65
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 1 mg (700070P-1mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand
• Lipid-Typ: bile acids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• InChI: 1S/C27H46O5/c1-15(6-5-7-16(2)25(31)32)19-8-9-20-24-21(14-23(30)27(19,20)4)26(3)11-10-18(28)12-17(26)13-22(24)29/h15-24,28-30H,5-14H2,1-4H3,(H,31,32)/t15-,16?,17+,18-,19-,20+,21+,22-,23+,24+,26+,27-/m1/s1
• InChIKey: CNWPIIOQKZNXBB-VCVMUKOKSA-N

Beschreibung

Allgemeine Beschreibung

Trihydroxycholestanoic acid (THCA) is an oxidative metabolite of cholesterol and a precursor to bile acids. Very long-chain acyl-CoA synthetase (VLCS) associated with endoplasmic reticulum and peroxisomes activates THCA, the C27 bile acid intermediate.

Anwendung

Trihydroxycholestanoic acid has been used as a sterol to test its reactivity with human mincle protein.

Biochem./physiol. Wirkung

Trihydroxycholestanoic acid (THCA) and dihydroxycholestanoic (DHCA) accumulation is observed in Zellweger syndrome and cholestatic liver disease. The synthesis of (25R)-isomer of DHCA and THCA is favored by mitochondrial 27-hydroxylase.

Verpackung

5 mL Amber Glass Screw Cap Vial (700070P-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): No data available
• Flammpunkt (°C): No data available