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Merck

C4790

Sigma-Aldrich

Carbenoxolon Dinatriumsalz

≥98%

Synonym(e):

3β-Hydroxy-11-oxoolean-12-en-30-oic acid 3-hemisuccinate

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About This Item

Lineare Formel:
C34H48O7Na2
CAS-Nummer:
Molekulargewicht:
614.72
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352108
PubChem Substanz-ID:
NACRES:
NA.22

Qualitätsniveau

Assay

≥98%

Form

powder

Lagertemp.

2-8°C

SMILES String

[Na].[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]3(C)C2=CC(=O)[C@]4([H])[C@@]5(C)CC[C@H](OC(=O)CCC(O)=O)C(C)(C)[C@]5([H])CC[C@@]34C)C(O)=O

InChI

1S/C34H50O7.2Na/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6;;/h18,21,23-24,27H,8-17,19H2,1-7H3,(H,36,37)(H,39,40);;/q;2*+1/p-2/t21-,23?,24-,27+,30+,31?,32-,33+,34+;;/m0../s1

InChIKey

BQENDLAVTKRQMS-FDPMUVMVSA-L

Allgemeine Beschreibung

Carbenoxolone disodium is a water soluble disodium salt of glycyrrhetinic acid hemisuccinate. It acts as an efficient promoter for the nasal absorption of insulin.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Eye Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Current biology : CB, 28(10), 1585-1594 (2018-05-15)
Animals detect changes in the environment using modality-specific, peripheral sensory neurons. The insect gustatory system encodes tastant identity and concentration through the independent firing of gustatory receptor neurons (GRNs) that spike rapidly at stimulus onset and quickly adapt. Here, we
Promotion of nasal absorption of insulin by glycyrrhetinic acid derivatives. I.
Mishima M, et al.
Journal of Pharmacobio-Dynamics, 12(1), 31-36 (1989)
Seo-Yeon Yoon et al.
The journal of pain : official journal of the American Pain Society, 14(2), 205-214 (2013-02-05)
Spinal glial cells contribute to the development of many types of inflammatory and neuropathic pain. Here the contribution of spinal astrocytes and astrocyte gap junctions to oxaliplatin-induced mechanical hypersensitivity was explored. The expression of glial fibrillary acidic protein (GFAP) in
R A Warwick et al.
European journal of pain (London, England), 17(4), 571-580 (2012-10-16)
Chemotherapy-induced peripheral neuropathy is a serious side effect in cancer treatment, a major manifestation being neuropathic pain that can be debilitating and can reduce the quality of life of the patient. Oxaliplatin and taxol are common anti-cancer drugs that induce
André T Shimoyama et al.
Naunyn-Schmiedeberg's archives of pharmacology, 386(1), 5-14 (2012-11-07)
Chlorogenic acid (CGA) is found in many foods, including coffee, berries, potatoes, carrots, wine, apples, and various herbs, and has anti-inflammatory, antidiabetic, and antitumoral actions. The CGA is well absorbed orally, and its effects on gastric ulcer have not been

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