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86720

Sigma-Aldrich

Tetraethylthiuramdisulfid

≥97.0% (S)

Synonym(e):

Bis-(diethylthiocarbamoyl)-disulfid, Bis-(diethylthiocarbamyl)-disulfid, Disulfiram, TETD

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About This Item

Lineare Formel:
(C2H5)2NCSS2CSN(C2H5)2
CAS-Nummer:
97-77-8
Molekulargewicht:
296.54
Beilstein:
1712560
EG-Nummer:
202-607-8
MDL-Nummer:
MFCD00009048
UNSPSC-Code:
12352100
PubChem Substanz-ID:
57653188
NACRES:
NA.22

Qualitätsniveau

200

Assay

≥97.0% (S)

Form

powder

mp (Schmelzpunkt)

69-71 °C (lit.)

SMILES String

CCN(CC)C(=S)SSC(=S)N(CC)CC

InChI

1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3

InChIKey

AUZONCFQVSMFAP-UHFFFAOYSA-N

Angaben zum Gen

human ... ALDH2(217) , CYP1A2(1544)

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Verwandte Kategorien

Anwendung

Alkoholdehydrogenase-Inhibitor

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT RE 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Analysenzertifikate (COA)

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Sigma-Aldrich

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Sigma-Aldrich

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Disulfiram (DS), an anti-alcoholism medicine, shows strong anti-cancer activity in the laboratory, but the application in clinics for anti-cancer therapy has been limited by its prompt metabolism. Conventional liposomes have shown limited ability to protect DS. Therefore, the aim of
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The safety, immunogenicity, impact on the latent reservoir and rebound of viral load after therapeutic HIV-1 vaccination with recombinant modified vaccinia Ankara-based (MVA-B) HIV-1 vaccine expressing monomeric gp120 and the fused Gag-Pol-Nef polyprotein of clade B with or without a
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The major approach to the development of anticancer drugs involves searching for new compounds, efficient against malignancies, which are not, as yet, used clinically. This strategy is time-consuming and expensive. Recent studies have disclosed a surprising, but mechanistically consistent, anticancer
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Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(6), 953-960 (2013-04-26)
Disulfiram has been used for several decades in the treatment of alcoholism. It now shows promise as an anticancer drug and radiosensitizer. Proposed mechanisms of action include the induction of oxidative stress and inhibition of proteasome activity. Our purpose was
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