791806

Yu-Wasa-Hilfsstoff

97%

• Synonym(e): 2,3,5,6-Tetrafluor-4-(trifluormethyl)-anilin, 2,3,5,6,α,α,α-Heptafluor-p-toluidin
• Lineare Formel: CF₃C₆F₄NH₂
• CAS-Nummer: 651-83-2
• Molekulargewicht: 233.09
• Beilstein: 2657893
• MDL-Nummer: MFCD00091518
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 329768293
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: liquid
• Eignung der Reaktion: reaction type: C-C Bond Formation; reagent type: catalyst; reaction type: C-H Activation
• Brechungsindex: n20/D 1.431 (lit.); n20/D 1.432
• bp: 186 °C (lit.)
• Dichte: 1.662 g/mL at 25 °C; 1.687 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: fluoro
• SMILES String: Nc1c(F)c(F)c(c(F)c1F)C(F)(F)F
• InChI: 1S/C7H2F7N/c8-2-1(7(12,13)14)3(9)5(11)6(15)4(2)10/h15H2
• InChIKey: FJOACTZFMHZHSC-UHFFFAOYSA-N

Beschreibung

Sonstige Hinweise

Acidic amides are superior directing groups for promoting C-H activation reactions with both Pd(0)/PR₃ and Pd(II) catalysts.

Used in the Preparation of

• Lactams via palladium-catalyzed olefination of arylamides with benzylacrylate, followed by 1,4-conjugate addition
• N-(fluorinated aryl)benzamides as substrates for regioselective C-H amination reactions with O-benzoylhydroxylamines
• Substituted succinimides via palladium-catalyzed carbonylation of N-aryl amides
• N-aryl cyclopropanecarboxamide substrates and various amino acid ligands for palladium-catalyzed C-H activation of cyclopropanes

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable