761591

(4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine hydrochloride

95%

• Synonym(e): Benzylamino tetrazine hydrochloride, H-Tz-Bz-NH₃Cl hydrochloride
• Empirische Formel (Hill-System): C₉H₉N₅ · xHCl
• CAS-Nummer: 1345866-68-3
• Molekulargewicht: 187.20 (free base basis)
• MDL-Nummer: MFCD23097050
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 329766561
• NACRES: NA.22

Eigenschaften

• Assay: 95%
• Form: solid
• Eignung der Reaktion: reaction type: click chemistry; reagent type: linker
• mp (Schmelzpunkt): 206-225 °C (decomposition)
• Funktionelle Gruppe: amine
• Lagertemp.: −20°C
• SMILES String: NCC1=CC=C(C2=NN=CN=N2)C=C1.[H]Cl
• InChI: 1S/C9H9N5.ClH/c10-5-7-1-3-8(4-2-7)9-13-11-6-12-14-9;/h1-4,6H,5,10H2;1H
• InChIKey: FAAUXGMWUKVOPI-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine is a 1,2,4,5-tetrazine derivative capable of undergoing [4+2] Diels-Alder cycloaddition reactions with strained alkenes, which makes it highly useful in bioorthogonal labeling and cell detection applications.

Anwendung

Amine functionalized tetrazine for inverse electron demand Diels-Alder cycloaddition reactions. The tetrazine will react with strained alkenes such as transcyclooctene, norbornene and cyclopropene to yield a stable covalent linkage. Tetrazines have proven useful in bioorthogonal reactions for many biological imaging and bioconjugation applications.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301 - H315 - H319 - H335
• P-Sätze: P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable