761060

(Tributylphosphoranylidene)acetonitrile

97%

• Synonym(e): (Cyanomethylene)tributylphosphorane
• Empirische Formel (Hill-System): C₁₄H₂₈NP
• CAS-Nummer: 157141-27-0
• Molekulargewicht: 241.35
• MDL-Nummer: MFCD01321151
• UNSPSC-Code: 12352000
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Form: liquid
• Brechungsindex: n20/D 1.500 (lit.)
• Dichte: 0.921 g/mL at 25 °C
• Lagertemp.: 2-8°C
• SMILES String: [P](=CC#N)(CCCC)(CCCC)CCCC
• InChI: 1S/C14H28NP/c1-4-7-11-16(14-10-15,12-8-5-2)13-9-6-3/h14H,4-9,11-13H2,1-3H3
• InChIKey: OZMLUMPWPFZWTP-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

(Tributylphosphoranylidene)acetonitrile or cyanomethylenetrimethylphosphorane (Bu₃P=CHCN) is a Wittig reagent employed in the transformation of the carbonyl compounds, including aldehydes, esters, and lactones into the corresponding unsaturated nitriles.

Anwendung

(Tributylphosphoranylidene)acetonitrile can be utilized as a reagent in the:

• Stereoselective synthesis of skytanthine and other O- and N-containing heterocycles by Mitsunobu intramolecular cycloalkylation.
• Wittig olefination of esters, lactones, N-Boc lactam, and cyclic imide to corresponding Wittig products.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable