731013

2-{Bis-[3,5-bis-(trifluoromethyl)-phenyl]-phosphino}-3,6-dimethoxy-2′,4′,6′-triisopropyl-1,1′-biphenyl

95%

• Synonym(e): Bis-(3,5-bis-(trifluormethyl)-phenyl)-(2′,4′,6′- triisopropyl-3,6-dimethoxybiphenyl-2-yl)-phosphin, JackiePhos
• Empirische Formel (Hill-System): C₃₉H₃₇F₁₂O₂P
• CAS-Nummer: 1160861-60-8
• Molekulargewicht: 796.66
• MDL-Nummer: MFCD17015286
• UNSPSC-Code: 12352112
• PubChem Substanz-ID: 329764613
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: solid
• Eignung der Reaktion: reaction type: Cross Couplings; reagent type: ligand; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reagent type: ligand; reaction type: C-X Bond Formation
• mp (Schmelzpunkt): 186-190 °C
• Funktionelle Gruppe: phosphine
• SMILES String: COc1ccc(OC)c(c1P(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)-c4c(cc(cc4C(C)C)C(C)C)C(C)C
• InChI: 1S/C39H37F12O2P/c1-19(2)22-11-29(20(3)4)33(30(12-22)21(5)6)34-31(52-7)9-10-32(53-8)35(34)54(27-15-23(36(40,41)42)13-24(16-27)37(43,44)45)28-17-25(38(46,47)48)14-26(18-28)39(49,50)51/h9-21H,1-8H3
• InChIKey: KYTUFIMHJNRPLC-UHFFFAOYSA-N

Beschreibung

Anwendung

Catalyst for N-Arylation reactions

Buchwald Phosphine Ligands for chemical Synthesis

JackiePhos is a Buchwald′s phosphine ligand which can be used for the:

• glycosyl cross-coupling reaction of diaryliodonium triflates with anomeric stannanes to synthesize C-glycosides.
• synthesis of gold-based catalyst complexes such as [Au(CH₃CN)(JackiePhos)][SbF₆] and [(JackiePhos)AuCl.
• acylation of alkylcarbastannatranes.
• synthesis of cyclic guanidines or cyclic ureas bearing dialkylaminomethyl groups in combination with Pd(acac)₂ as a catalyst.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable