648418

(−)-DIP-Chlorid^™ -Lösung

50-65 wt. % in heptane

• Synonym(e): (−)-B-Chlorodiisopinocampheylborane, (−)-Chlorodiisopinocampheylborane, Chlorobis[(1R,2S,3R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]borane, Diisopinocampheylchloroborane
• Empirische Formel (Hill-System): C₂₀H₃₄BCl
• CAS-Nummer: 85116-37-6
• Molekulargewicht: 320.75
• MDL-Nummer: MFCD00074807
• UNSPSC-Code: 12352001
• PubChem Substanz-ID: 24883579
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Konzentration: 50-65 wt. % in heptane
• Dichte: 0.895 g/mL at 25 °C
• SMILES String: C[C@H]1[C@@H](C[C@@H]2C[C@H]1C2(C)C)B(Cl)[C@@H]3C[C@@H]4C[C@H]([C@H]3C)C4(C)C
• InChI: 1S/C20H34BCl/c1-11-15-7-13(19(15,3)4)9-17(11)21(22)18-10-14-8-16(12(18)2)20(14,5)6/h11-18H,7-10H2,1-6H3/t11-,12-,13+,14+,15-,16-,17-,18-/m1/s1
• InChIKey: PSEHHVRCDVOTID-VMAIWCPRSA-N

Beschreibung

Allgemeine Beschreibung

(−)-DIP-Chloride^™ solution is a pinane-based asymmetric reducing agent that is commonly used in asymmetric reduction reactions.

Anwendung

(−)-Diisopinocampheylchloroborane [(−)-DIP-Chloride^™] solution can be used as a reducing reagent for the:

• Enantioselective reduction of α, β-unsaturated trifluoromethyl ketones into corresponding secondary allylic alcohols.
• Asymmetric reduction of aromatic and aliphatic α-halomethyl ketones to haloalcohols.

It can also be used as a catalyst for the enantioselective asymmetric Pictet-Spengler reaction.

Rechtliche Hinweise

DIP-Chloride is a trademark of Sigma-Aldrich Co. LLC

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS05,GHS07,GHS09
• Signalwort: Danger
• H-Sätze: H225,H304,H314,H336,H410
• P-Sätze: P210 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): <-22.0 °F - closed cup
• Flammpunkt (°C): < -30 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter