636401

Phthalylglycylchlorid

96%

• Synonym(e): 1,3-Dioxo-2-isoindolineacetyl chloride, NSC 401729, Phthalylglycine acid chloride
• Empirische Formel (Hill-System): C₁₀H₆ClNO₃
• CAS-Nummer: 6780-38-7
• Molekulargewicht: 223.61
• EG-Nummer: 229-840-8
• MDL-Nummer: MFCD00192872
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24882779
• NACRES: NA.22

Eigenschaften

• Assay: 96%
• Form: solid
• SMILES String: ClC(=O)CN1C(=O)c2ccccc2C1=O
• InChI: 1S/C10H6ClNO3/c11-8(13)5-12-9(14)6-3-1-2-4-7(6)10(12)15/h1-4H,5H2
• InChIKey: RHZBRCQIKQUQHQ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Phthalylglycyl chloride can be synthesized via reaction of phthalyl-glycine with thionyl chloride.

Anwendung

Phthalylglycyl chloride can be used in the synthesis of N-Phthalimidoacetyl-β-phenylethylamnine.

Reactant involved in:

• Synthesis of selenium-containing amino acid analogs with bactericidal and antifungal activity
• Photoinduced single electron transfer cyclization for preparation of cyclic peptides
• Arndt-Eistert synthesis
• Mitsunobu and arbuzov-type multicomponent pathway
• Remote C-H bond functionalization
• Amido-alkylation for synthesis of benzofuran derivatives

Sicherheitshinweise

• Piktogramme: GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H301,H314
• P-Sätze: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Gefahreneinstufungen: Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges