540110

(R)-(−)-Glycidyl-p-toluolsulfonat

98%

• Synonym(e): (2R)-(−)-Glycidyltosylat, (R)-(−)-p-Toluolsulfonsäure-2,3-epoxypropylester, (R)-(−)-Glycidyl-tosylat, (R)-(−)-Oxiran-2-methanol-p-toluolsulfonat
• Empirische Formel (Hill-System): C₁₀H₁₂O₄S
• CAS-Nummer: 113826-06-5
• Molekulargewicht: 228.26
• Beilstein: 3592142
• MDL-Nummer: MFCD00010834
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24878442
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 98%
• mp (Schmelzpunkt): 46-49 °C (lit.)
• Funktionelle Gruppe: ether; tosylate
• Lagertemp.: 2-8°C
• SMILES String: Cc1ccc(cc1)S(=O)(=O)OC[C@H]2CO2
• InChI: 1S/C10H12O4S/c1-8-2-4-10(5-3-8)15(11,12)14-7-9-6-13-9/h2-5,9H,6-7H2,1H3/t9-/m1/s1
• InChIKey: NOQXXYIGRPAZJC-SECBINFHSA-N

Beschreibung

Anwendung

(2R)-(-)-Glycidyl tosylate may be used to prepare:

• 1-O-hexadecyl-sn-glycerol 3-O-p-toluenesulfonate by reacting with 1-hexadecanol in the presence of boron trifluoride etherate.
• 4-Oxiranylmethoxy-(1H)-indole by reacting with 4-hydroxyindole in the presence of sodium hydride.
• [¹⁸F]Epifluorohydin, an intermediate for preparing of [¹⁸F]fluoromisonidazole.

It can also be used as a starting material in the synthesis of 1,2-diacyl-sn-3-glycerophosphocholines.

Rechtliche Hinweise

Manufactured under license by Shasun Chemicals and Drugs Limited, using Jacobsen HKR technology.

Sicherheitshinweise

• Piktogramme: GHS08,GHS05,GHS07,GHS09
• Signalwort: Danger
• H-Sätze: H317,H318,H341,H350,H411
• P-Sätze: P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Aquatic Chronic 2 - Carc. 1B - Eye Dam. 1 - Muta. 2 - Skin Sens. 1
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): >230.0 °F
• Flammpunkt (°C): > 110 °C
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges