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DL-Homocystein-thiolacton -hydrochlorid
≥99.0% (AT)
Synonym(e):
DL-2-Amino-4-mercapto-buttersäure-1,4-thiolacton -hydrochlorid
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About This Item
Empirische Formel (Hill-System):
C4H7NOS · HCl
CAS-Nummer:
Molekulargewicht:
153.63
Beilstein:
3689338
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
eCl@ss:
42021308
PubChem Substanz-ID:
NACRES:
NA.22
Empfohlene Produkte
Qualitätsniveau
Assay
≥99.0% (AT)
Form
solid
Verlust
≤0.5% loss on drying
mp (Schmelzpunkt)
202 °C (dec.) (lit.)
~203 °C (dec.)
Funktionelle Gruppe
thioester
SMILES String
Cl[H].NC1CCSC1=O
InChI
1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H
InChIKey
ZSEGSUBKDDEALH-UHFFFAOYSA-N
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Allgemeine Beschreibung
DL-Homocysteine thiolactone hydrochloride (HTL-HCl) is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.
Anwendung
DL-Homocysteine thiolactone hydrochloride may be used in the preparation of:
- DL-buthionine
- DL-homocysteine
- poly[α,β-(N-2-aminoethyl-dl-aspartamide)]-poly[α,β-(N-2-hydroxyethyl-dl-aspartamide)]-poly[α,β-(N-3-mercapto-1-methoxycarbonyl-propyl-dl-aspartamide)] copolymer diclofenac conjugate (PAHMA-Dic)
- bis[ S-(dimethylarsino)homocysteine]
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - Skin Irrit. 2
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(11), 4023-4027 (2012-08-18)
Elevated concentration of homocysteine (Hcy) in human plasma, defined as hyperhomocysteinemia has been correlated with some diseases, such as cardiovascular, neurodegenerative, and kidney disorders. Homocysteine occurs in human plasma in several forms, including the most reactive form of Hcy -
Lukasz Marczak et al.
Journal of proteomics, 74(7), 967-974 (2011-02-19)
Elevated levels of homocysteine (Hcy) are associated with cardiovascular and neurodegenerative diseases in humans. Hcy becomes a component of human proteins as a result of N-homocysteinylation of protein lysine residues by Hcy-thiolactone, which affects the protein's structure and function, and
Reza Yousefi et al.
International journal of biological macromolecules, 51(3), 291-298 (2012-05-29)
In the current study both structural alteration and fibrillation of insulin were studied in the presence of homocysteine thiolactone (HCTL). The spectroscopic studies revealed that HCTL increases rate of insulin unfolding, giving rise to the appearance of solvent-exposed hydrophobic regions
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Resveratrol (3,4',5-trihydroxystilben), a phenolic antioxidant synthesized in grapes and other plants, and also present in wine, has been suggested to help prevent cardiovascular events. In this study the influence of resveratrol on platelet aggregation during a model of hyperhomocysteinemia was
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