Alle Fotos(1)

Wichtige Dokumente

Gesamtdokumentation anzeigen

532673

Castanospermin

Name: Castanospermin
Brand: ALDRICH

98%

Synonym(e):

(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidin, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidin, (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizintetrol, 1,6,7,8-Tetrahydroxy-octahydroindolizin

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Alle Fotos(1)

About This Item

Empirische Formel (Hill-System):

C₈H₁₅NO₄

CAS-Nummer:

79831-76-8

Molekulargewicht:

189.21

Beilstein:

3588654

MDL-Nummer:

MFCD00017555

UNSPSC-Code:

12352204

PubChem Substanz-ID:

24877905

NACRES:

NA.22

Empfohlene Produkte

Slide 1 of 10

1 of 10

Sigma-Aldrich

218775

Castanospermin, Castanospermum australe

Sigma-Aldrich

X100

Triton^™ X-100

Sigma-Aldrich

267511

Wolfram

Sigma-Aldrich

357421

Wolfram

Sigma-Aldrich

T8787

Triton^™ X-100

Sigma-Aldrich

262846

Tantal

$Albumin aus Rinderserum heat shock fraction, protease free, fatty acid free, essentially globulin free, pH 7, ≥98%$

Sigma-Aldrich

A7030

Albumin aus Rinderserum

Sigma-Aldrich

258806

7,12-Diethyl-3,8,13,17-tetramethyl-21H,23H-porphin-2,18-dipropionsäure -dihydrochlorid

Sigma-Aldrich

SML0306

Biapenem

Sigma-Aldrich

569747

Grubbs Catalyst^® M204

Qualitätsniveau

200

Assay

98%

Optische Aktivität

[α]20/D +80°, c = 0.9 in H₂O

mp (Schmelzpunkt)

213-217 °C (lit.)

Funktionelle Gruppe

hydroxyl

SMILES String

[H][C@]12[C@@H](O)CCN1C[C@H](O)[C@@H](O)[C@@H]2O

InChI

1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s1

InChIKey

JDVVGAQPNNXQDW-TVNFTVLESA-N

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Suche nach COA

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Efficient synthesis of (+)-1,8,8a-tri-epi-swainsonine, (+)-1,2-di-epi-lentiginosine, (+)-9a-epi-homocastanospermine and (-)-9-deoxy-9a-epi-homocastanospermine from a D-glucose-derived aziridine carboxylate, and study of their glycosidase inhibitory activities.

K S Ajish Kumar et al.

Organic & biomolecular chemistry, 6(4), 703-711 (2008-02-12)

The utility of a D-glucose-derived aziridine carboxylate was demonstrated for the synthesis of polyhydroxylated quinolizidine and indolizidine alkaloids. The chemoselective reduction of 1 followed by two-carbon homologation by the Wittig reaction afforded gamma,delta-aziridino-alpha,beta-unsaturated ester 9, which on regioselective nucleophilic aziridine

Asymmetric [2 + 2] cycloaddition: total synthesis of (-)-swainsonine and (+)-6-epicastanospermine.

Julien Ceccon et al.

Organic letters, 8(21), 4739-4742 (2006-10-06)

[reaction: see text] An asymmetric total synthesis of (-)-swainsonine and (+)-6-epicastanospermine is described from a common intermediate, which is obtained through diastereoselective [2 + 2] cycloaddition of dichloroketene to a chiral enol ether.

Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial.

Satoru Watanabe et al.

Antiviral research, 96(1), 32-35 (2012-08-08)

Celgosivir (6-O-butanoyl castanospermine), a pro-drug of the naturally occurring castanospermine, is an inhibitor of α-glucosidase I and II that is found to be a potent inhibitor of several enveloped viruses including all four serotypes of dengue virus. We showed previously

Synthesis of 1-deoxy-1-hydroxymethyl- and 1-deoxy-1-epi-hydroxymethyl castanospermine as new potential immunomodulating agents.

Vinod P Vyavahare et al.

Journal of medicinal chemistry, 50(22), 5519-5523 (2007-10-09)

Two new C-1 epimeric hydroxymethyl castanospermine congeners 2a and 2b, synthesized by stereocontrolled intramolecular double reductive amination of D-glucose derived beta-keto ester as a key step, showed impressive immuno-potentiating property. The bioactivity was mediated through up-regulation of T(H1)/T(H2) cytokine ratio.

A flexible approach to azasugars: asymmetric total syntheses of (+)-castanospermine, (+)-7-deoxy-6-epi-castanospermine, and (+)-1-epi-castanospermine.

Gang Liu et al.

Chemistry (Weinheim an der Bergstrasse, Germany), 16(19), 5755-5768 (2010-04-10)

The asymmetric total synthesis of natural azasugars (+)-castanospermine, (+)-7-deoxy-6-epi-castanospermine, and synthetic (+)-1-epi-castanospermine has been accomplished in nine to ten steps from a common chiral building block (S)-8. The method features a powerful chiral relay strategy consisting of a highly diastereoselective

Alle zugehörigen Dokumente anzeigen

Global Trade Item Number

SKU	GTIN
532673-1G
532673-100MG	4061832986357

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.

Wichtige Dokumente

Castanospermin

98%

About This Item

Empfohlene Produkte

Eigenschaften

Qualitätsniveau

Assay

Optische Aktivität

mp (Schmelzpunkt)

Funktionelle Gruppe

SMILES String

InChI

InChIKey

Verwandte Kategorien

Sicherheitshinweise

Lagerklassenschlüssel

WGK

Flammpunkt (°F)

Flammpunkt (°C)

Persönliche Schutzausrüstung

Dokumentation

Analysenzertifikate (COA)

Besitzen Sie dieses Produkt bereits?

Peer-Reviewed-Artikel

Global Trade Item Number

Technischer Dienst