513830

Indol-5-carboxaldehyd

98%

• Synonym(e): 5-Formylindole
• Empirische Formel (Hill-System): C₉H₇NO
• CAS-Nummer: 1196-69-6
• Molekulargewicht: 145.16
• MDL-Nummer: MFCD02093664
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24873717
• NACRES: NA.22

Eigenschaften

• Assay: 98%
• mp (Schmelzpunkt): 100-103 °C (lit.)
• SMILES String: O=Cc1ccc2[nH]ccc2c1
• InChI: 1S/C9H7NO/c11-6-7-1-2-9-8(5-7)3-4-10-9/h1-6,10H
• InChIKey: ADZUEEUKBYCSEY-UHFFFAOYSA-N

Beschreibung

Anwendung

Indole-5-carboxaldehyde can be used as a reactant in the:

• Preparation of curcumin derivatives as anti-proliferative & anti-inflammatory agents
• Preparation of analogs of botulinum neurotoxin serotype A protease inhibitors
• Stereoselective synthesis of dibenzylideneacetone derivatives as β-amyloid imaging probes
• Synthesis of para-para stilbenophanes by McMurry coupling
• Stereoselective synthesis of heteroaromatic (E)-α,β-unsaturated ketones from aldehydes
• Structure-based drug design of aurora kinase A inhibitors
• Preparation of 5-indolyl linked 15- and 18-membered azacrown ethers to study their cation-π interactions.
• Preparation of bibenzimidazole derivatives substituted 5-indolyl moiety in the study of inhibition of topoisomerase I activity.
• Synthesis of (5-(4-(3,4,5-trimethoxybenzoyl)-1H-imidazol-2-yl)-1H-indol-2-yl)(3,4,5-trimethoxyphenyl)methanone and radioiodinated indolochalcone.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves