470791

2,6-Difluorphenylborsäure

98%

• Lineare Formel: F₂C₆H₃B(OH)₂
• CAS-Nummer: 162101-25-9
• Molekulargewicht: 157.91
• MDL-Nummer: MFCD00792436
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24870682
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• mp (Schmelzpunkt): 147-149 °C (lit.)
• Funktionelle Gruppe: fluoro
• SMILES String: OB(O)c1c(F)cccc1F
• InChI: 1S/C6H5BF2O2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,10-11H
• InChIKey: DBZAICSEFBVFHL-UHFFFAOYSA-N

Beschreibung

Anwendung

2,6-Difluorophenylboronic acid can be used:

• As a substrate in the model reaction of Suzuki–Miyaura coupling with 4-chloro-3-methylanisole.
• To prepare 4-bromo-2,3′,5′,6-tetrafluorobiphenyl, a key intermediate for the synthesis of 2,6-difluorinated oligophenyls applicable in organic semiconductors.
• To prepare ethyl 4-(2,6-difluorophenyl)nicotinate, a key intermediate for the synthesis of 4-phenyl pyridine based potent TGR5 agonists.

Sonstige Hinweise

Contains varying amounts of the anhydride

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves