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421669

Sigma-Aldrich

Asp-Phe

96%, for peptide synthesis

Synonym(e):

Aspartamsäure, N-L-α-Aspartyl-L-phenylalanin

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About This Item

Lineare Formel:
HOOCCH2CH(NH2)CONHCH(CH2C6H5)CO2H
CAS-Nummer:
13433-09-5
Molekulargewicht:
280.28
Beilstein:
2817528
EG-Nummer:
236-557-3
MDL-Nummer:
MFCD00063155
UNSPSC-Code:
12352209
PubChem Substanz-ID:
24866392
NACRES:
NA.22

product name

Asp-Phe, 96%

Assay

96%

Form

powder

Optische Aktivität

[α]20/D +12.5°, c = 1 in 0.5 M HCl

Eignung der Reaktion

reaction type: solution phase peptide synthesis

mp (Schmelzpunkt)

236-239 °C (lit.)

Anwendung(en)

peptide synthesis

SMILES String

N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C13H16N2O5/c14-9(7-11(16)17)12(18)15-10(13(19)20)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7,14H2,(H,15,18)(H,16,17)(H,19,20)/t9-,10-/m0/s1

InChIKey

YZQCXOFQZKCETR-UWVGGRQHSA-N

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Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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L-Phenylalanin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1100

L-Phenylalanin

Aspartam United States Pharmacopeia (USP) Reference Standard

USP

1043706

Aspartam

Aspartam analytical standard

Supelco

47135

Aspartam

Methylmyristat analytical standard

Supelco

70129

Methylmyristat

L-Phenylalanin BioUltra, ≥99.0% (NT)

Sigma-Aldrich

78019

L-Phenylalanin

S S Leung et al.
Journal of pharmaceutical sciences, 86(1), 64-71 (1997-01-01)
Some solid-state pharmaceutical properties and the solid-state thermal stability of the model dipeptides aspartame (APM) and aspartylphenylalanine (AP), have been investigated. Studies by differential scanning calorimetry (DSC), thermal gravimetric analysis (TGA), high-performance liquid chromatography, powder X-ray diffraction, and optical microscopy
E A Timokhina et al.
Prikladnaia biokhimiia i mikrobiologiia, 23(3), 426-428 (1987-05-01)
A technique for quantitative determining of the synthetic sweetener aspartame. NH2-Asp-Phe-OMe and its hydrolysis product, NH2-Asp-Phe-OH, is proposed based on the use of an amino acid analyzer.
E G Burton et al.
The Journal of nutrition, 119(5), 713-721 (1989-05-01)
A new beta-aspartyl dipeptide, N-beta-L-aspartyl-L-phenylalanine (beta-AP), has been isolated and identified in urine and plasma from normal human volunteers. beta-AP was isolated from urine samples by high performance liquid chromatography (HPLC). Its identity and stereochemistry were demonstrated by HPLC and
Tao Wang et al.
Biomolecules, 9(11) (2019-11-27)
Short oligopeptides are some of the most promising and functionally important amide bond-containing components, with widespread applications. Biosynthesis of these oligopeptides may potentially become the ultimate strategy because it has better cost efficiency and environmental-friendliness than conventional solid phase peptide
N A Tobey et al.
Gastroenterology, 91(4), 931-937 (1986-10-01)
Aspartame [Nutrasweet, Equal (Searle Consumer Products, Chicago, Ill.)] is the methyl ester of the dipeptide aspartylphenylalanine (Asp-Phe). After hydrolysis of the ester bond in the intestinal lumen, the dipeptide is apparently absorbed and digested in the same manner as dipeptides
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