349720

(3-Carboxypropyl)-triphenylphosphoniumbromid

98%

• Synonym(e): (4-Hydroxy-4-oxobutyl)triphenylphosphonium bromide
• Lineare Formel: HO₂C(CH₂)₃P(C₆H₅)₃Br
• CAS-Nummer: 17857-14-6
• Molekulargewicht: 429.29
• MDL-Nummer: MFCD00274196
• UNSPSC-Code: 12352002
• PubChem Substanz-ID: 24861704
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• Eignung der Reaktion: reaction type: C-C Bond Formation
• mp (Schmelzpunkt): 244-247 °C (lit.)
• SMILES String: [Br-].OC(=O)CCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C22H21O2P.BrH/c23-22(24)17-10-18-25(19-11-4-1-5-12-19,20-13-6-2-7-14-20)21-15-8-3-9-16-21;/h1-9,11-16H,10,17-18H2;1H
• InChIKey: NKVJKVMGJABKHV-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for preparation of:

• Piperamide analogs as histone deacetylase (HDAC) inhibitors with antitumor activity
• Boron-containing benzoxaboroles as antimalarial agents
• Methyl alkenyl quinolones as antimycobacterial agents
• Solandelactone E via Sharpless epoxidation, Taber cyclopropanation, chemoselective reductions and lithiation-borylation-allylation sequence
• Organotin compounds as antifungal agents
• Oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B for negative regulation of insulin pathway (a promising target for treatment of diabetes and obesity)
• 11-oxa prostaglandin analogs with ocular hypotensive activity

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves