226289

N,N-Dimethyltrimethylsilylamin

97%

• Synonym(e): N-(Trimethylsilyl)-dimethylamin, Dimethylaminotrimethylsilan, TMSDMA
• Lineare Formel: (CH₃)₃SiN(CH₃)₂
• CAS-Nummer: 2083-91-2
• Molekulargewicht: 117.26
• Beilstein: 1731861
• EG-Nummer: 218-222-3
• MDL-Nummer: MFCD00008297
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24853554
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 97%
• Form: liquid
• Brechungsindex: n20/D 1.397 (lit.)
• bp: 84 °C (lit.)
• Dichte: 0.732 g/mL at 25 °C (lit.)
• SMILES String: CN(C)[Si](C)(C)C
• InChI: 1S/C5H15NSi/c1-6(2)7(3,4)5/h1-5H3
• InChIKey: KAHVZNKZQFSBFW-UHFFFAOYSA-N

Beschreibung

Anwendung

N,N-Dimethyltrimethylsilylamine can be used as a reactant to prepare:

• Trifluoromethylacetophenone-N,N-dimethyltrimethylsilylamine adduct, which is used as an efficient reagent for nucleophilic trifluoromethylation of carbonyl and the imine group.
• (Dimethylamino)sulfur trifluoride (Me-DAST), which is employed as a deoxofluorinating agent for the conversion of aliphatic alcohols into their corresponding fluorides.
• Nucleoside phosphoramidites by reacting with alkyloxy (or aryloxy)-triazolylphosphine and deoxynucleoside.

It can also be used as a silylating agent in chemical synthesis.

Sicherheitshinweise

• Piktogramme: GHS02,GHS05
• Signalwort: Danger
• H-Sätze: H225 - H260 - H314
• P-Sätze: P210 - P223 - P231 + P232 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - Water-react 1
• Lagerklassenschlüssel: 4.3 - Hazardous materials, which set free flammable gases upon contact with water
• WGK: WGK 3
• Flammpunkt (°F): 10.4 °F - closed cup
• Flammpunkt (°C): -12 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter