193984

1-Methylindol

≥97%

• Synonym(e): NSC 212534
• Empirische Formel (Hill-System): C₉H₉N
• CAS-Nummer: 603-76-9
• Molekulargewicht: 131.17
• Beilstein: 111026
• EG-Nummer: 210-057-5
• MDL-Nummer: MFCD00005800
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24851625
• NACRES: NA.22

Eigenschaften

• Assay: ≥97%
• Form: liquid
• Brechungsindex: n20/D 1.606 (lit.)
• bp: 133 °C/26 mmHg (lit.)
• Dichte: 1.051 g/mL at 20 °C (lit.)
• SMILES String: Cn1ccc2ccccc12
• InChI: 1S/C9H9N/c1-10-7-6-8-4-2-3-5-9(8)10/h2-7H,1H3
• InChIKey: BLRHMMGNCXNXJL-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

1-Methylindole undergoes Au(III)/TPPMS-catalyzed benzylation reaction with benzhydryl and benzylic alcohols.

Anwendung

1-Methylindole was used in the determination of association constant for the electron-donor-acceptor complexes of 1-methylindole with 1-(2,4,6-trinitrophenyl) propan-2-one.

Reactant for preparation of:

• Pharmaceutically active 2-oxo-1-pyrrolidine analogues
• Non-receptor tyrosine kinase (Src kinase) inhibitors
• PET agents for imaging of protein kinase C (PKC)
• Ynediones as highly reactive Michael systems
• Anticancer agents
• Polycyclic derivatives of indoles
• PET agents for imaging of glycogen synthase kinase-3 (GSK-3)
• Anti-prion disease agents
• Bisindole derivatives with antihyperlipidemic activity
• PET cancer imaging agents

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)